Reciprocal regulation of mesenchymal stem cells and immune responses
Mesenchymal stem/stromal cells (MSCs) exist in almost all tissues and participate in tissue
regeneration and homeostasis. In-vitro-expanded MSCs are employed as therapeutics for …
regeneration and homeostasis. In-vitro-expanded MSCs are employed as therapeutics for …
[HTML][HTML] Mesenchymal stromal cells: putative microenvironmental modulators become cell therapy
M Krampera, K Le Blanc - Cell stem cell, 2021 - cell.com
An exceptional safety profile has been shown in a large number of cell therapy clinical trials
that use mesenchymal stromal cells (MSCs). However, reliable potency assays are still …
that use mesenchymal stromal cells (MSCs). However, reliable potency assays are still …
Mesenchymal stem cell secretome as an emerging cell-free alternative for improving wound repair
The use of mesenchymal stem cells (MSC) for the treatment of cutaneous wounds is
currently of enormous interest. However, the broad translation of cell therapies into clinical …
currently of enormous interest. However, the broad translation of cell therapies into clinical …
Treatment of COVID-19-associated ARDS with mesenchymal stromal cells: a multicenter randomized double-blind trial
Background Severe acute respiratory syndrome coronavirus-2 (SARS–CoV-2)-induced
acute respiratory distress syndrome (ARDS) causes high mortality. Umbilical cord-derived …
acute respiratory distress syndrome (ARDS) causes high mortality. Umbilical cord-derived …
Paracrine mechanisms of mesenchymal stromal cells in angiogenesis
S Maacha, H Sidahmed, S Jacob… - Stem cells …, 2020 - Wiley Online Library
The role of the mesenchymal stromal cell‐(MSC‐) derived secretome is becoming
increasingly intriguing from a clinical perspective due to its ability to stimulate endogenous …
increasingly intriguing from a clinical perspective due to its ability to stimulate endogenous …
Effects of mesenchymal stem cell‐derived paracrine signals and their delivery strategies
Mesenchymal stem cells (MSCs) have been widely studied as a versatile cell source for
tissue regeneration and remodeling due to their potent bioactivity, which includes …
tissue regeneration and remodeling due to their potent bioactivity, which includes …
Therapeutic properties of mesenchymal stromal/stem cells: the need of cell priming for cell-free therapies in regenerative medicine
Mesenchymal stromal/stem cells (MSCs) are multipotent adult stem cells that support
homeostasis during tissue regeneration. In the last decade, cell therapies based on the use …
homeostasis during tissue regeneration. In the last decade, cell therapies based on the use …
Murine macrophages or their secretome delivered in alginate dressings enhance impaired wound healing in diabetic mice
Diabetic foot ulceration is a devastating diabetic complication with unmet needs. We
explored the efficacy of calcium-crosslinked alginate dressings in topically delivering …
explored the efficacy of calcium-crosslinked alginate dressings in topically delivering …
Comparing the therapeutic potential of stem cells and their secretory products in regenerative medicine
Cell therapy involves the transplantation of human cells to replace or repair the damaged
tissues and modulate the mechanisms underlying disease initiation and progression in the …
tissues and modulate the mechanisms underlying disease initiation and progression in the …
Mesenchymal stromal cells as critical contributors to tissue regeneration
GD Sagaradze, NA Basalova, AY Efimenko… - Frontiers in cell and …, 2020 - frontiersin.org
Adult stem cells that are tightly regulated by the specific microenvironment, or the stem cell
niche, function to maintain tissue homeostasis and regeneration after damage. This …
niche, function to maintain tissue homeostasis and regeneration after damage. This …