Nanoparticle probes for the detection of cancer biomarkers, cells, and tissues by fluorescence

AB Chinen, CM Guan, JR Ferrer, SN Barnaby… - Chemical …, 2015 - ACS Publications
Cancer is the second most common cause of death in the United States, trailing only heart
disease in incidence. Despite significant worldwide investment in research, cancer remains …

Glycans and glycoproteins as specific biomarkers for cancer

MJ Kailemia, D Park, CB Lebrilla - Analytical and bioanalytical chemistry, 2017 - Springer
Protein glycosylation and other post-translational modifications are involved in potentially all
aspects of human growth and development. Defective glycosylation has adverse effects on …

The diagnostic performance of CA125 for the detection of ovarian and non-ovarian cancer in primary care: A population-based cohort study

G Funston, W Hamilton, G Abel, EJ Crosbie… - PLoS …, 2020 - journals.plos.org
Background The serum biomarker cancer antigen 125 (CA125) is widely used as an
investigation for possible ovarian cancer in symptomatic women presenting to primary care …

Clinical use of cancer biomarkers in epithelial ovarian cancer: updated guidelines from the European Group on Tumor Markers

G Sölétormos, MJ Duffy, SOA Hassan… - International Journal of …, 2016 - ijgc.bmj.com
Objective To present an update of the European Group on Tumor Markers guidelines for
serum markers in epithelial ovarian cancer. Methods Systematic literature survey from 2008 …

Current and emerging methods for ovarian cancer screening and diagnostics: a comprehensive review

JM Liberto, SY Chen, IM Shih, TH Wang, TL Wang… - Cancers, 2022 - mdpi.com
Simple Summary Ovarian high-grade serous carcinoma (HGSC) has a 5-year survival rate
of less than 50%, making it one of the most lethal gynecological cancers for women in the …

A risk of malignancy index incorporating CA 125, ultrasound and menopausal status for the accurate preoperative diagnosis of ovarian cancer

I Jacobs, D Oram, J Fairbanks, J Turner… - … Journal of Obstetrics …, 1990 - Wiley Online Library
Age, ultrasound score, menopausal status, a clinical impression score and serum CA 125
level were assessed to see how they could best distinguish between patients with benign …

A novel multiple marker bioassay utilizing HE4 and CA125 for the prediction of ovarian cancer in patients with a pelvic mass

RG Moore, DS McMeekin, AK Brown, P DiSilvestro… - Gynecologic …, 2009 - Elsevier
INTRODUCTION: Patients diagnosed with epithelial ovarian cancer (EOC) have improved
outcomes when cared for at centers experienced in the management of EOC. The objective …

The HE4 (WFDC2) protein is a biomarker for ovarian carcinoma

I Hellstrom, J Raycraft, M Hayden-Ledbetter… - Cancer research, 2003 - AACR
Abstract The WFDC2 (HE4) gene is amplified in ovarian carcinomas, whereas its expression
in normal tissues, including ovary, is low. Although the function of the HE4 protein is …

Design of the prostate, lung, colorectal and ovarian (PLCO) cancer screening trial

PC Prorok, GL Andriole, RS Bresalier, SS Buys… - Controlled clinical …, 2000 - Elsevier
The objectives of the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial are to
determine in screenees ages 55–74 at entry whether screening with flexible sigmoidoscopy …

A novel electrochemical immunosensor for ultrasensitive detection of CA125 in ovarian cancer

PS Pakchin, M Fathi, H Ghanbari, R Saber… - Biosensors and …, 2020 - Elsevier
In the current study, we report on the design and development of a novel electrochemical
immunosensor for the detection of cancer antigen 125 (CA125) oncomarker …