[HTML][HTML] Calcium channels and their role in regenerative medicine
N Ahamad, BB Singh - World Journal of Stem Cells, 2021 - ncbi.nlm.nih.gov
Stem cells hold indefinite self-renewable capability that can be differentiated into all desired
cell types. Based on their plasticity potential, they are divided into totipotent (morula stage …
cell types. Based on their plasticity potential, they are divided into totipotent (morula stage …
Mitochondrial calcium homeostasis in hematopoietic stem cell: Molecular regulation of quiescence, function, and differentiation
Hematopoiesis is based on the existence of hematopoietic stem cells (HSC) with the
capacity to self-proliferate and self-renew or to differentiate into specialized cells. The …
capacity to self-proliferate and self-renew or to differentiate into specialized cells. The …
Exploring the potential of predicted miRNAs on the genes involved in the expansion of hematopoietic stem cells
A major challenge in therapeutic approaches applying hematopoietic stem cells (HSCs) is
the cell quantity. The primary objective of this study was to predict the miRNAs and anti …
the cell quantity. The primary objective of this study was to predict the miRNAs and anti …
Novel differential calcium regulation of hematopoietic stem and progenitor cells under physiological low oxygen conditions
P Dausinas Ni, M Hartman, J Slack… - Journal of Cellular …, 2023 - Wiley Online Library
Low oxygen bone marrow (BM) niches (~ 1%–4% low O2) provide critical signals for
hematopoietic stem/progenitor cells (HSC/HSPCs). Our presented data are the first to …
hematopoietic stem/progenitor cells (HSC/HSPCs). Our presented data are the first to …
Differential activation of Ca2+ influx channels modulate stem cell potency, their proliferation/viability and tissue regeneration
N Ahamad, Y Sun… - NPJ Regenerative …, 2021 - nature.com
Stem cells have indefinite self-renewable capability; however, factors that modulate their
pluripotency/function are not fully identified. Here we show that store-dependent Ca2+ entry …
pluripotency/function are not fully identified. Here we show that store-dependent Ca2+ entry …
BML‐260 promotes the growth of cord blood and mobilized peripheral blood hematopoietic stem and progenitor cells with improved reconstitution ability
Hematopoietic stem cells (HSCs), which are multipotent and have the ability to self‐renew,
are frequently used in the treatment of hematological diseases and cancer. Small molecules …
are frequently used in the treatment of hematological diseases and cancer. Small molecules …
[HTML][HTML] The role of calcium-sensing receptor in ginsenoside Rg1 promoting reendothelialization to inhibit intimal hyperplasia after balloon injury
S Xu, A Hu, J Chen, Z Shuai, T Liu, J Deng, L Li… - Biomedicine & …, 2023 - Elsevier
Calcium-sensing receptor (CaSR) is a G protein-coupled receptor, widely distributed in
various tissues, including vascular endothelial cells and smooth muscle cells, which plays …
various tissues, including vascular endothelial cells and smooth muscle cells, which plays …
[HTML][HTML] Stromal interaction molecule 1-mediated store-operated calcium entry promotes autophagy through AKT/mammalian target of rapamycin pathway in …
H Zhang, W Xie, Y Feng, J Wei, C Yang, P Luo, Y Yang… - Neuroscience, 2023 - Elsevier
The pathophysiological process of neuronal injury due to cerebral ischemia is complex
among which disturbance of calcium homeostasis and autophagy are two major …
among which disturbance of calcium homeostasis and autophagy are two major …
Ginsenosides on stem cells fate specification—a novel perspective
Y Liu, L Jiang, W Song, C Wang, S Yu… - Frontiers in Cell and …, 2023 - frontiersin.org
Recent studies have demonstrated that stem cells have attracted much attention due to their
special abilities of proliferation, differentiation and self-renewal, and are of great significance …
special abilities of proliferation, differentiation and self-renewal, and are of great significance …
Competitive inhibition of IL-2/IL-2R has a dual effect on HSC ex vivo expansion and IL-2R (CD25) content
Abstract Interleukin-2 (IL-2) and its receptor play a pivotal role in the regulation of immune
response and possess both immune-regulatory and immune-stimulatory functions. As a …
response and possess both immune-regulatory and immune-stimulatory functions. As a …