[HTML][HTML] Calcium channels and their role in regenerative medicine

N Ahamad, BB Singh - World Journal of Stem Cells, 2021 - ncbi.nlm.nih.gov
Stem cells hold indefinite self-renewable capability that can be differentiated into all desired
cell types. Based on their plasticity potential, they are divided into totipotent (morula stage …

Mitochondrial calcium homeostasis in hematopoietic stem cell: Molecular regulation of quiescence, function, and differentiation

M Bonora, A Kahsay, P Pinton - International Review of Cell and Molecular …, 2021 - Elsevier
Hematopoiesis is based on the existence of hematopoietic stem cells (HSC) with the
capacity to self-proliferate and self-renew or to differentiate into specialized cells. The …

Exploring the potential of predicted miRNAs on the genes involved in the expansion of hematopoietic stem cells

M Elahimanesh, N Shokri, R Shabani, M Rahimi… - Scientific Reports, 2024 - nature.com
A major challenge in therapeutic approaches applying hematopoietic stem cells (HSCs) is
the cell quantity. The primary objective of this study was to predict the miRNAs and anti …

Novel differential calcium regulation of hematopoietic stem and progenitor cells under physiological low oxygen conditions

P Dausinas Ni, M Hartman, J Slack… - Journal of Cellular …, 2023 - Wiley Online Library
Low oxygen bone marrow (BM) niches (~ 1%–4% low O2) provide critical signals for
hematopoietic stem/progenitor cells (HSC/HSPCs). Our presented data are the first to …

Differential activation of Ca2+ influx channels modulate stem cell potency, their proliferation/viability and tissue regeneration

N Ahamad, Y Sun… - NPJ Regenerative …, 2021 - nature.com
Stem cells have indefinite self-renewable capability; however, factors that modulate their
pluripotency/function are not fully identified. Here we show that store-dependent Ca2+ entry …

BML‐260 promotes the growth of cord blood and mobilized peripheral blood hematopoietic stem and progenitor cells with improved reconstitution ability

E Albayrak, S Akgol, RD Turan, M Uslu… - Journal of Cellular …, 2022 - Wiley Online Library
Hematopoietic stem cells (HSCs), which are multipotent and have the ability to self‐renew,
are frequently used in the treatment of hematological diseases and cancer. Small molecules …

[HTML][HTML] The role of calcium-sensing receptor in ginsenoside Rg1 promoting reendothelialization to inhibit intimal hyperplasia after balloon injury

S Xu, A Hu, J Chen, Z Shuai, T Liu, J Deng, L Li… - Biomedicine & …, 2023 - Elsevier
Calcium-sensing receptor (CaSR) is a G protein-coupled receptor, widely distributed in
various tissues, including vascular endothelial cells and smooth muscle cells, which plays …

[HTML][HTML] Stromal interaction molecule 1-mediated store-operated calcium entry promotes autophagy through AKT/mammalian target of rapamycin pathway in …

H Zhang, W Xie, Y Feng, J Wei, C Yang, P Luo, Y Yang… - Neuroscience, 2023 - Elsevier
The pathophysiological process of neuronal injury due to cerebral ischemia is complex
among which disturbance of calcium homeostasis and autophagy are two major …

Ginsenosides on stem cells fate specification—a novel perspective

Y Liu, L Jiang, W Song, C Wang, S Yu… - Frontiers in Cell and …, 2023 - frontiersin.org
Recent studies have demonstrated that stem cells have attracted much attention due to their
special abilities of proliferation, differentiation and self-renewal, and are of great significance …

Competitive inhibition of IL-2/IL-2R has a dual effect on HSC ex vivo expansion and IL-2R (CD25) content

M Uslu, E Albayrak, F Kocabaş - International Immunopharmacology, 2022 - Elsevier
Abstract Interleukin-2 (IL-2) and its receptor play a pivotal role in the regulation of immune
response and possess both immune-regulatory and immune-stimulatory functions. As a …