The RAS pathway participates in the cascade of proliferation and cell division process, and
the activated RAS pathway can lead to tumorigenesis including hepatocellular carcinoma …

Background Although the sphingolipid metabolism pathway is known to play a significant
role in tumor progression, there have been few studies on how genetic variants in the …

Hepatocellular carcinoma (HCC) ranks the third leading cause of cancer deaths with a
dismal 5‐year survival rate. The mitogen‐activated protein kinase (MAPK) signaling …

Disulfidptosis is a novel form of programmed cell death involved in migration and invasion of
cancer cells, but few studies investigated the roles of genetic variants in disulfidptosis …

According to reports, MAP3K14 is considered an oncogene and is aberrantly expressed in
various types of tumor cells. Its abnormal expression is closely associated with the …

Hepatocellular carcinoma (HCC) is one of the most common malignant tumors with a high
mortality rate. The 5-methylcytosine (m5C), a type of RNA modification, plays crucial …

Abstract N6‐methyladenosine (m6A) is a dynamic and reversible modification process
involving in a series of important biological and pathophysiological processes, including the …

The nuclear factor E2-related factor 2 (NRF2) signaling pathway is one of the most important
cell defense pathways. However, it is unclear whether genetic variants in NRF2 signaling …

Background Ferroptosis is a known crucial player in the development of cancers. However,
the effect of single nucleotide polymorphisms (SNPs) in ferroptosis‐related genes on …

Purpose P53 is a suppressor gene closely related to carcinogenesis. However, the
associations between genetic variants in the p53 signaling pathway and prognosis in …