Individuals suffering from depressive disorders display a greater incidence of hypertension
compared with the general population, despite reports of the association between …

Major depressive disorder (MDD) is a highly prevalent and disabling disorder. Despite the
many hypotheses proposed to understand the molecular pathophysiology of depression, it is …

Orthostatic hypotension (OH) is an abnormal blood pressure response to standing, which is
associated with an increased risk of adverse outcomes such as syncope, falls, cognitive …

The monoamine hypothesis of depression posits that an imbalance in monoaminergic
neurotransmission is causally related to the clinical features of depression. Antidepressants …

The consumption of antidepressants has increased on a global scale. These medications
are frequently prescribed to treat mental health-related disorders and their usage is …

Introduction: There is a well-established relationship between sexual functioning and quality
of life. Depression can cause sexual dysfunction (SD) and its treatment can often lead to …

Psychiatric disorders and sleep problems are both common, with an estimated prevalence in
12 months of about 30% for any of the Diagnostic and Statistical Manual of Mental …

The triazole ring system has emerged as an exciting prospect in the optimization studies of
promising lead molecules in the quest for new drugs for clinical usage. Several marketed …

Individual patients with depression present with unique symptom clusters–before, during,
and even after treatment. The prevalence of persistent, unresolved symptoms and their …

Trazodone is an antidepressant that is FDA-approved for the treatment of depression. It has
been used by mental health and primary care providers for the treatment of multiple …