Ribosomes are highly conserved ribonucleoprotein nanomachines that translate information
in the genome to create the proteome in all cells. In yeast these complex particles contain …

The essential cellular process of ribosome biogenesis is at the nexus of various signalling
pathways that coordinate protein synthesis with cellular growth and proliferation. The fact …

Non-small cell lung cancer (NSCLC) has the highest mortality rate among all malignancies
worldwide. The role of long noncoding RNAs (lncRNAs) in the progression of cancers is a …

Mitochondria play a central role in cellular energy provision. The organelles contain their
own genome with a modified genetic code. The mammalian mitochondrial genome is …

tRNA biology has come of age, revealing an unprecedented level of understanding and
many unexpected discoveries along the way. This review highlights new findings on the …

The discovery that mutations in mitochondrial DNA (mtDNA) can be pathogenic in humans
has increased interest in understanding mtDNA maintenance. The functional state of mtDNA …

Some mitochondrial long noncoding RNAs (lncRNAs) are encoded by nuclear DNA, but the
mechanisms that mediate their transport to mitochondria are poorly characterized. Using …

We have identified gas5 (growth arrest-specific transcript 5) as a non-protein-coding multiple
small nucleolar RNA (snoRNA) host gene similar to UHG (U22 host gene). Encoded within …

▪ Abstract The synthesis of ribosomes is one of the major metabolic pathways in all cells. In
addition to around 75 individual ribosomal proteins and 4 ribosomal RNAs, synthesis of a …

Extracellular vesicles (EVs) play an important role in the biology of various organisms,
including fungi, in which they are required for the trafficking of molecules across the cell wall …