E3 ligases and deubiquitinating enzymes regulating the MAPK signaling pathway in cancers
HB Park, KH Baek - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2022 - Elsevier
The mitogen-activated protein kinase (MAPK) signaling pathway is the primary regulatory
module of various cellular processes such as cell proliferation, differentiation, and stress …
module of various cellular processes such as cell proliferation, differentiation, and stress …
Insights of crosstalk between p53 protein and the MKK3/MKK6/p38 MAPK signaling pathway in cancer
L Stramucci, A Pranteda, G Bossi - Cancers, 2018 - mdpi.com
TP53 is universally recognized as a pivotal protein in cell-cycle fate and apoptotic induction
and, unsurprisingly, it is one of the most commonly hijacked control mechanisms in cancer …
and, unsurprisingly, it is one of the most commonly hijacked control mechanisms in cancer …
[HTML][HTML] MicroRNA-378 suppresses myocardial fibrosis through a paracrine mechanism at the early stage of cardiac hypertrophy following mechanical stress.
J Yuan, H Liu, W Gao, L Zhang, Y Ye, L Yuan… - Theranostics, 2018 - ncbi.nlm.nih.gov
Rationale: Excessive myocardial fibrosis is the main pathological process in the
development of cardiac remodeling and heart failure; therefore, it is important to prevent …
development of cardiac remodeling and heart failure; therefore, it is important to prevent …
[HTML][HTML] LncRNA PTTG3P promotes tumorigenesis and metastasis of NSCLC by binding with ILF3 to maintain mRNA stability and form a positive feedback loop with …
J Wang, X He, Q Yao, C Wang, X Lu… - … Journal of Biological …, 2023 - ncbi.nlm.nih.gov
Non-small cell lung cancer (NSCLC) is a highly lethal disease worldwide. We found the
pseudogene-derived lncRNA PTTG3P is upregulated in NSCLC and associated with larger …
pseudogene-derived lncRNA PTTG3P is upregulated in NSCLC and associated with larger …
ZnO nanostructures based biosensors for cancer and infectious disease applications: Perspectives, prospects and promises
SS Bhat, A Qurashi, FA Khanday - TrAC Trends in Analytical Chemistry, 2017 - Elsevier
ZnO nanostructures have attracted great attention from researchers due to their fascinating
properties that include high surface-area, better crystallinity, and improved optical and …
properties that include high surface-area, better crystallinity, and improved optical and …
Discovery of a covalent kinase inhibitor from a DNA-encoded small-molecule library× protein library selection
AI Chan, LM McGregor, T Jain… - Journal of the American …, 2017 - ACS Publications
We previously reported interaction determination using unpurified proteins (IDUP), a method
to selectively amplify DNA sequences encoding ligand: target pairs from a mixture of DNA …
to selectively amplify DNA sequences encoding ligand: target pairs from a mixture of DNA …
Loss-of-function uORF mutations in human malignancies
J Schulz, N Mah, M Neuenschwander, T Kischka… - Scientific reports, 2018 - nature.com
Ribosome profiling revealed widespread translational activity at upstream open reading
frames (uORFs) and validated uORF-mediated translational control as a commonly …
frames (uORFs) and validated uORF-mediated translational control as a commonly …
Understanding cytotoxicity and cytostaticity in a high-throughput screening collection
LH Mervin, Q Cao, IP Barrett, MA Firth… - ACS chemical …, 2016 - ACS Publications
While mechanisms of cytotoxicity and cytostaticity have been studied extensively from the
biological side, relatively little is currently understood regarding areas of chemical space …
biological side, relatively little is currently understood regarding areas of chemical space …
Synthesis, characterization and applications of magnetic iron oxide nanostructures
Magnetic iron oxide nanoparticles (MIONPs) have been extensively utilized for several
applications that include catalysis (artificial enzymes, nanozyme), renewable energy …
applications that include catalysis (artificial enzymes, nanozyme), renewable energy …
Prognostic biomarkers related to breast cancer recurrence identified based on Logit model analysis
X Zhou, C Xiao, T Han, S Qiu, M Wang, J Chu… - World journal of surgical …, 2020 - Springer
Background This study intended to determine important genes related to the prognosis and
recurrence of breast cancer. Methods Gene expression data of breast cancer patients were …
recurrence of breast cancer. Methods Gene expression data of breast cancer patients were …