Design of therapeutic biomaterials to control inflammation

Z Tu, Y Zhong, H Hu, D Shao, R Haag… - Nature Reviews …, 2022 - nature.com
Inflammation plays an important role in the response to danger signals arising from damage
to our body and in restoring homeostasis. Dysregulated inflammatory responses occur in …

Mito‐bomb: targeting mitochondria for cancer therapy

X Guo, N Yang, W Ji, H Zhang, X Dong… - Advanced …, 2021 - Wiley Online Library
Cancer has been one of the most common life‐threatening diseases for a long time.
Traditional cancer therapies such as surgery, chemotherapy (CT), and radiotherapy (RT) …

A thrombin‐activated peptide‐templated nanozyme for remedying ischemic stroke via thrombolytic and neuroprotective actions

Z Wang, Y Zhao, Y Hou, G Tang, R Zhang… - Advanced …, 2024 - Wiley Online Library
Ischemic stroke (IS) is one of the most common causes of disability and death. Thrombolysis
and neuroprotection are two current major therapeutic strategies to overcome ischemic and …

Alzheimer's disease and its treatment by different approaches: A review

S Srivastava, R Ahmad, SK Khare - European Journal of Medicinal …, 2021 - Elsevier
Alzheimer's disease (AD) is a neurodegenerative disorder that impairs mental ability
development and interrupts neurocognitive function. This neuropathological condition is …

Reactive oxygen species (ROS)-based nanomedicine

B Yang, Y Chen, J Shi - Chemical reviews, 2019 - ACS Publications
Reactive oxygen species (ROS) play an essential role in regulating various physiological
functions of living organisms. The intrinsic biochemical properties of ROS, which underlie …

Nanozymes: classification, catalytic mechanisms, activity regulation, and applications

Y Huang, J Ren, X Qu - Chemical reviews, 2019 - ACS Publications
Because of the high catalytic activities and substrate specificity, natural enzymes have been
widely used in industrial, medical, and biological fields, etc. Although promising, they often …

Nanomaterials with enzyme-like characteristics (nanozymes): next-generation artificial enzymes (II)

J Wu, X Wang, Q Wang, Z Lou, S Li, Y Zhu… - Chemical Society …, 2019 - pubs.rsc.org
Nanozymes are nanomaterials with enzyme-like characteristics (Chem. Soc. Rev., 2013, 42,
6060–6093). They have been developed to address the limitations of natural enzymes and …

Concepts of nanoparticle cellular uptake, intracellular trafficking, and kinetics in nanomedicine

ND Donahue, H Acar, S Wilhelm - Advanced drug delivery reviews, 2019 - Elsevier
Nanoparticle-based therapeutics and diagnostics are commonly referred to as
nanomedicine and may significantly impact the future of healthcare. However, the clinical …

An overview of the use of nanozymes in antibacterial applications

L Mei, S Zhu, Y Liu, W Yin, Z Gu, Y Zhao - Chemical Engineering Journal, 2021 - Elsevier
Topics of bacterial resistance have attracted remarkable scientific interests. Bacterial
infection-related diseases are major public safety issues that lead to millions of deaths …

Recent advances in nanozyme research

H Wang, K Wan, X Shi - Advanced materials, 2019 - Wiley Online Library
As a new generation of artificial enzymes, nanozymes have the advantages of high catalytic
activity, good stability, low cost, and other unique properties of nanomaterials. Due to their …