Purpose Macrophages are highly plastic cells. Under different stimuli, macrophages can be
polarized into several different subsets. Two main macrophage subsets have been …

Obesity is increasingly prevalent and is associated with substantial cardiovascular risk.
Adipose tissue distribution and morphology play a key role in determining the degree of …

Lactate dehydrogenase (LDH) is a terminating enzyme in the metabolic pathway of
anaerobic glycolysis with end product of lactate from glucose. The lactate formation is crucial …

With increasing age, the immune system undergoes a remodeling process, termed
immunosenescence, which is accompanied by considerable shifts in leukocyte …

Significance: Macrophages are crucial for tissue homeostasis. Based on their activation,
they might display classical/M1 or alternative/M2 phenotypes. M1 macrophages produce pro …

Purpose Obesity is a leading modifiable contributor to breast cancer mortality due to its
association with increased recurrence and decreased overall survival rate. Obesity …

Microglial activation and neuroinflammatory changes are characteristic of the aged brain
and contribute to age-related cognitive impairment. Exercise improves cognitive function in …

Subclinical inflammation is linked to comorbidities and risk factors, consolidating the
diagnosis of chronic non-communicable diseases, such as insulin resistance …

Obesity is a major risk factor for asthma. Likewise, obesity is known to increase disease
severity in asthmatic subjects and also to impair the efficacy of first-line treatment …

Aims Increasing adipose tissue capillarization is beneficial to metabolic health. The present
study examined the effects of continuous training (CT) and aerobic-interval training (AIT) …