Matrix stiffness regulates macrophage polarization in atherosclerosis

Y Wang, R Shi, R Zhai, S Yang, T Peng, F Zheng… - Pharmacological …, 2022 - Elsevier
Atherosclerosis is a chronic inflammatory disease and the pathological basis of many fatal
cardiovascular diseases. Macrophages, the main inflammatory cells in atherosclerotic …

Epigenetic regulation of ferroptosis in central nervous system diseases

T Lan, TT Sun, C Wei, T Cheng, F Yang, JN Zhang… - Molecular …, 2023 - Springer
Ferroptosis, a newly identified form of cell death, is characterized by iron overload and
accumulation of lipid reactive oxygen species. Inactivation of pathways, such as glutathione …

PRMT5 activates AKT via methylation to promote tumor metastasis

L Huang, XO Zhang, EJ Rozen, X Sun, B Sallis… - Nature …, 2022 - nature.com
Abstract Protein arginine methyltransferase 5 (PRMT5) is the primary methyltransferase
generating symmetric-dimethyl-arginine marks on histone and non-histone proteins. PRMT5 …

ALK signaling primes the DNA damage response sensitizing ALK-driven neuroblastoma to therapeutic ATR inhibition

M Borenäs, G Umapathy, DE Lind… - Proceedings of the …, 2024 - National Acad Sciences
High-risk neuroblastoma (NB) is a significant clinical challenge. MYCN and Anaplastic
Lymphoma Kinase (ALK), which are often involved in high-risk NB, lead to increased …

Metastasis pattern and prognosis in children with neuroblastoma

S Liu, W Yin, Y Lin, S Huang, S Xue, G Sun… - World Journal of Surgical …, 2023 - Springer
Background We aimed to investigate the different metastases and prognoses of
neuroblastoma (NB) and determine the risk factors of metastasis. Method Data of 1224 …

[HTML][HTML] Advances in epigenetic modifications and cervical cancer research

H Liu, H Ma, Y Li, H Zhao - Biochimica et Biophysica Acta (BBA)-Reviews …, 2023 - Elsevier
Cervical cancer (CC) is an important public health problem for women, and perspectives
and information regarding its prevention and treatment are quickly evolving. Human …

SMARCE1 promotes neuroblastoma tumorigenesis through assisting MYCN-mediated transcriptional activation

X Hu, R Liu, J Hou, W Peng, S Wan, M Xu, Y Li… - Oncogene, 2022 - nature.com
SMARCE1 gene, encoding a core subunit of SWI/SNF chromatin remodeling complex, is
situated on chromosome 17q21-ter region that is frequently gained in neuroblastoma …

Chromosome Imbalances in Neuroblastoma—Recent Molecular Insight into Chromosome 1p-deletion, 2p-gain, and 11q-deletion Identifies New Friends and Foes for …

J Guan, B Hallberg, RH Palmer - Cancers, 2021 - mdpi.com
Simple Summary Neuroblastoma is a pediatric cancer that arises in the sympathetic nervous
system. High-risk neuroblastoma is clinically challenging and identification of novel …

A light-operated dual-mode method for neuroblastoma diagnosis based on a Tb-MOF: from biometabolite detection to logic devices

Y Liu, W Dan, B Yan - Inorganic Chemistry Frontiers, 2023 - pubs.rsc.org
Exploring simple analytical techniques with high accuracy and reliability to quantify
biomolecules is crucial, but it remains a great challenge for disease diagnosis. Since the …

Molecular basis and clinical features of neuroblastoma

J Takita - JMA journal, 2021 - jstage.jst.go.jp
Neuroblastoma, a neoplasm of the sympathetic nervous system, originates from
neuroblastoma stem cells during embryogenesis. It exhibits unique clinical features …