Self-assembling peptide and protein amyloids: from structure to tailored function in nanotechnology
Self-assembled peptide and protein amyloid nanostructures have traditionally been
considered only as pathological aggregates implicated in human neurodegenerative …
considered only as pathological aggregates implicated in human neurodegenerative …
Prebiotic peptides: Molecular hubs in the origin of life
The fundamental roles that peptides and proteins play in today's biology makes it almost
indisputable that peptides were key players in the origin of life. Insofar as it is appropriate to …
indisputable that peptides were key players in the origin of life. Insofar as it is appropriate to …
Machine learning overcomes human bias in the discovery of self-assembling peptides
Peptide materials have a wide array of functions, from tissue engineering and surface
coatings to catalysis and sensing. Tuning the sequence of amino acids that comprise the …
coatings to catalysis and sensing. Tuning the sequence of amino acids that comprise the …
Stimuli-responsive, pentapeptide, nanofiber hydrogel for tissue engineering
Short peptides are uniquely versatile building blocks for self-assembly. Supramolecular
peptide assemblies can be used to construct functional hydrogel biomaterials—an attractive …
peptide assemblies can be used to construct functional hydrogel biomaterials—an attractive …
Exploring the sequence space for (tri-) peptide self-assembly to design and discover new hydrogels
PWJM Frederix, GG Scott, YM Abul-Haija… - Nature …, 2015 - nature.com
Peptides that self-assemble into nanostructures are of tremendous interest for biological,
medical, photonic and nanotechnological applications. The enormous sequence space that …
medical, photonic and nanotechnological applications. The enormous sequence space that …
Design of nanostructures based on aromatic peptide amphiphiles
S Fleming, RV Ulijn - Chemical Society Reviews, 2014 - pubs.rsc.org
Aromatic peptide amphiphiles are gaining popularity as building blocks for the bottom-up
fabrication of nanomaterials, including gels. These materials combine the simplicity of small …
fabrication of nanomaterials, including gels. These materials combine the simplicity of small …
Root of the tree: the significance, evolution, and origins of the ribosome
The ribosome is an ancient molecular fossil that provides a telescope to the origins of life.
Made from RNA and protein, the ribosome translates mRNA to coded protein in all living …
Made from RNA and protein, the ribosome translates mRNA to coded protein in all living …
Fabrication of novel biomaterials through molecular self-assembly
S Zhang - Nature biotechnology, 2003 - nature.com
Two complementary strategies can be used in the fabrication of molecular biomaterials. In
the'top-down'approach, biomaterials are generated by stripping down a complex entity into …
the'top-down'approach, biomaterials are generated by stripping down a complex entity into …
Casting metal nanowires within discrete self-assembled peptide nanotubes
Tubular nanostructures are suggested to have a wide range of applications in
nanotechnology. We report our observation of the self-assembly of a very short peptide, the …
nanotechnology. We report our observation of the self-assembly of a very short peptide, the …
Atomic structures of amyloid cross-β spines reveal varied steric zippers
MR Sawaya, S Sambashivan, R Nelson, MI Ivanova… - Nature, 2007 - nature.com
Amyloid fibrils formed from different proteins, each associated with a particular disease,
contain a common cross-β spine. The atomic architecture of a spine, from the fibril-forming …
contain a common cross-β spine. The atomic architecture of a spine, from the fibril-forming …