[HTML][HTML] A review exploring biological activities of hydrazones

G Verma, A Marella, M Shaquiquzzaman… - Journal of Pharmacy …, 2014 - journals.lww.com
The development of novel compounds, hydrazones has shown that they possess a wide
variety of biological activities viz. antimicrobial, anticonvulsant, antidepressant, anti …

[HTML][HTML] Mini-review of the importance of hydrazides and their derivatives—Synthesis and biological activity

SN Mali, BR Thorat, DR Gupta, A Pandey - Engineering proceedings, 2021 - mdpi.com
Organic acid hydrazides include a vast group of organic derivatives of hydrazines containing
the active functional group (-C (= O) NHNH2). Acid hydrazones were important bidentate …

Tetrazole hybrids with potential anticancer activity

J Zhang, S Wang, Y Ba, Z Xu - European journal of medicinal chemistry, 2019 - Elsevier
Cancer is one of the main causes of death throughout the world. The anticancer agents are
indispensable for the treatment of various cancers, but most of them currently on the market …

Synthesis, carbonic anhydrase inhibitory activity, anticancer activity and molecular docking studies of new imidazolyl hydrazone derivatives

M Tapera, H Kekeçmuhammed, B Tüzün… - Journal of molecular …, 2022 - Elsevier
A new series of imidazolyl hydrazone derivatives IA (1-12) were prepared from a
condensation reaction between indoline-2, 3-dione (isatin) and 2 …

Identification of a new class of antifungals targeting the synthesis of fungal sphingolipids

V Mor, A Rella, AM Farnoud, A Singh, M Munshi… - MBio, 2015 - Am Soc Microbiol
Recent estimates suggest that> 300 million people are afflicted by serious fungal infections
worldwide. Current antifungal drugs are static and toxic and/or have a narrow spectrum of …

MAO enzymes inhibitory activity of new benzimidazole derivatives including hydrazone and propargyl side chains

ÖD Can, D Osmaniye, ÜD Özkay, BN Sağlık… - European journal of …, 2017 - Elsevier
In the present work, 15 new N'-(arylidene)-4-(1-(prop-2-yn-1-yl)-1H-benzo [d] imidazol-2-yl)
benzohydrazide (4a-4o) were designed and synthesized. The structures of the synthesized …

Synthesis, molecular modeling, in vivo study, and anticancer activity of 1,2,4‐triazole containing hydrazide–hydrazones derived from (S)‐naproxen

Mİ Han, H Bekçi, AI Uba, Y Yıldırım… - Archiv der …, 2019 - Wiley Online Library
Abstract A new series of 1, 2, 4‐triazole containing hydrazide–hydrazones derived from (S)‐
naproxen (7a–m) was synthesized in this study. The structures of these compounds were …

A new series of hydrazones as small‐molecule aldose reductase inhibitors

MD Altıntop, Y Demir, C Türkeş, RB Öztürk… - Archiv der …, 2023 - Wiley Online Library
In the search for small‐molecule aldose reductase (AR) inhibitors, new tetrazole‐hydrazone
hybrids (1–15) were designed. An efficient procedure was employed for the synthesis of …

Synthesis, biological evaluation and molecular docking studies of chromone hydrazone derivatives as α-glucosidase inhibitors

G Wang, M Chen, J Wang, Y Peng, L Li, ZZ Xie… - Bioorganic & Medicinal …, 2017 - Elsevier
A series of chromone hydrazone derivatives 4a–4p have been synthesized, characterized
by 1 H NMR and 13 C NMR and evaluated for their in vitro α-glucosidase inhibitory activity …

Rapid 'one-pot'synthesis of a novel benzimidazole-5-carboxylate and its hydrazone derivatives as potential anti-inflammatory and antimicrobial agents

K Vasantha, G Basavarajaswamy, MV Rai… - Bioorganic & Medicinal …, 2015 - Elsevier
A novel series of N-arylidene-2-(2, 4-dichloro phenyl)-1-propyl-1H-benzo [d] imidazole-5-
carbohydrazides having different substitution on the arylidene part were synthesized in good …