[HTML][HTML] Traumatic spinal cord injury: an overview of pathophysiology, models and acute injury mechanisms

A Alizadeh, SM Dyck, S Karimi-Abdolrezaee - Frontiers in neurology, 2019 - frontiersin.org
Traumatic spinal cord injury (SCI) is a life changing neurological condition with substantial
socioeconomic implications for patients and their care-givers. Recent advances in medical …

Traumatic spinal cord injury—repair and regeneration

CS Ahuja, S Nori, L Tetreault, J Wilson, B Kwon… - …, 2017 - journals.lww.com
BACKGROUND: Traumatic spinal cord injuries (SCI) have devastating consequences for the
physical, financial, and psychosocial well-being of patients and their caregivers. Expediently …

The influence of timing of surgical decompression for acute spinal cord injury: a pooled analysis of individual patient data

JH Badhiwala, JR Wilson, CD Witiw, JS Harrop… - The Lancet …, 2021 - thelancet.com
Background Although there is a strong biological rationale for early decompression of the
injured spinal cord, the influence of the timing of surgical decompression for acute spinal …

Acute traumatic spinal cord injury

I Eli, DP Lerner, Z Ghogawala - Neurologic Clinics, 2021 - neurologic.theclinics.com
Acute traumatic spinal cord injury (SCI) is typically associated with devastating outcomes.
The injury to the spinal cord results in damage to motor, sensory, and autonomic functions of …

Spinal cord injury: molecular mechanisms and therapeutic interventions

X Hu, W Xu, Y Ren, Z Wang, X He, R Huang… - … and Targeted Therapy, 2023 - nature.com
Spinal cord injury (SCI) remains a severe condition with an extremely high disability rate.
The challenges of SCI repair include its complex pathological mechanisms and the …

Mesenchymal stem cell-derived exosomes: therapeutic opportunities and challenges for spinal cord injury

W Liu, Z Ma, J Li, X Kang - Stem cell research & therapy, 2021 - Springer
Spinal cord injury (SCI) often leads to serious motor and sensory dysfunction of the limbs
below the injured segment. SCI not only results in physical and psychological harm to …

Characterizing natural recovery after traumatic spinal cord injury

S Kirshblum, B Snider, F Eren, J Guest - Journal of neurotrauma, 2021 - liebertpub.com
The predominant tool used to predict outcomes after traumatic spinal cord injury (SCI) is the
International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI), in …

Modern medical management of spinal cord injury

M Karsy, G Hawryluk - Current Neurology and Neuroscience Reports, 2019 - Springer
Abstract Purpose of Review Spinal cord injury (SCI) shows an incidence of 10.4–83
cases/million/year globally and remains a significant source of morbidity and cost to society …

Time is spine: a review of translational advances in spinal cord injury: JNSPG 75th Anniversary Invited Review Article

JH Badhiwala, CS Ahuja, MG Fehlings - Journal of Neurosurgery: Spine, 2018 - thejns.org
Acute traumatic spinal cord injury (SCI) is a devastating event with far-reaching physical,
emotional, and economic consequences for patients, families, and society at large. Timely …

Neurological recovery following traumatic spinal cord injury: a systematic review and meta-analysis

MH Khorasanizadeh, M Yousefifard, M Eskian… - … of Neurosurgery: Spine, 2019 - thejns.org
OBJECTIVE Predicting neurological recovery following traumatic spinal cord injury (TSCI) is
a complex task considering the heterogeneous nature of injury and the inconsistency of …