Endogenous and exogenous antioxidants as a tool to ameliorate male infertility induced by reactive oxygen species
Significance: Antioxidants are essential for the maintenance of cellular redox
homeodynamics in the male reproductive tract, playing a key role in fertilizing potential …
homeodynamics in the male reproductive tract, playing a key role in fertilizing potential …
Promising potential of dietary (poly) phenolic compounds in the prevention and treatment of diabetes mellitus
Background: The incidence of diabetes mellitus (DM) is reaching alarming proportions
worldwide, particularly because it is increasingly affecting younger people. This reflects the …
worldwide, particularly because it is increasingly affecting younger people. This reflects the …
[HTML][HTML] Whole exome sequencing and in silico analysis of human Sertoli in patients with non-obstructive azoospermia
H Azizi, D Hashemi Karoii, T Skutella - International Journal of Molecular …, 2022 - mdpi.com
Non-obstructive azoospermia (NOA) is a serious cause of male infertility. The Sertoli cell
responds to androgens and takes on roles supporting spermatogenesis, which may cause …
responds to androgens and takes on roles supporting spermatogenesis, which may cause …
Dose-dependent effects of caffeine in human Sertoli cells metabolism and oxidative profile: relevance for male fertility
Caffeine is a widely consumed substance present in several beverages. There is an
increasing consumption of energetic drinks, rich in caffeine, among young individuals in …
increasing consumption of energetic drinks, rich in caffeine, among young individuals in …
Testosterone deficiency induced by progressive stages of diabetes mellitus impairs glucose metabolism and favors glycogenesis in mature rat Sertoli cells
The incidence of type 2 diabetes mellitus and its prodromal stage, pre-diabetes, is rapidly
increasing among young men, leading to disturbances in testosterone synthesis. However …
increasing among young men, leading to disturbances in testosterone synthesis. However …
[HTML][HTML] Impacts of immunometabolism on male reproduction
L Ye, W Huang, S Liu, S Cai, L Hong, W Xiao… - Frontiers in …, 2021 - frontiersin.org
The physiological process of male reproduction relies on the orchestration of
neuroendocrine, immune, and energy metabolism. Spermatogenesis is controlled by the …
neuroendocrine, immune, and energy metabolism. Spermatogenesis is controlled by the …
[HTML][HTML] The impact of rumen-protected l-arginine oral supplementation on libido, semen quality, reproductive organ biometry, and serum biochemical parameters of …
This study aimed to investigate the effect of oral supplementation of rumen-protected L-
arginine on semen quality, testes and accessory genital glands biometry in rams. Ten …
arginine on semen quality, testes and accessory genital glands biometry in rams. Ten …
Male fertility and obesity: are ghrelin, leptin and glucagon-like peptide-1 pharmacologically relevant?
Obesity is rising to unprecedented numbers, affecting a growing number of children,
adolescents and young adult men. These individuals face innumerous health problems …
adolescents and young adult men. These individuals face innumerous health problems …
White tea intake prevents prediabetes-induced metabolic dysfunctions in testis and epididymis preserving sperm quality
Prediabetes has been associated with alterations in male reproductive tract, especially in
testis and epididymis. Moreover, in vitro studies described a promising action of tea …
testis and epididymis. Moreover, in vitro studies described a promising action of tea …
[HTML][HTML] Glucose and glutamine handling in the Sertoli cells of transgenic rats overexpressing regucalcin: plasticity towards lactate production
Sertoli cells (SCs) possess the unparalleled ability to provide the germ line with growth
factors and nutrients. Although SCs can oxidize amino acids, eg, glutamine, they mostly …
factors and nutrients. Although SCs can oxidize amino acids, eg, glutamine, they mostly …