The first microbial colonizers of the human gut: composition, activities, and health implications of the infant gut microbiota

C Milani, S Duranti, F Bottacini, E Casey… - Microbiology and …, 2017 - Am Soc Microbiol
The human gut microbiota is engaged in multiple interactions affecting host health during
the host's entire life span. Microbes colonize the neonatal gut immediately following birth …

[HTML][HTML] IL-6 and IL-8: an overview of their roles in healthy and pathological pregnancies

A Vilotić, M Nacka-Aleksić, A Pirković… - International journal of …, 2022 - mdpi.com
Interleukin-6 (IL-6) is an acknowledged inflammatory cytokine with a pleiotropic action,
mediating innate and adaptive immunity and multiple physiological processes, including …

[HTML][HTML] Maternal-fetal inflammation in the placenta and the developmental origins of health and disease

JA Goldstein, K Gallagher, C Beck, R Kumar… - Frontiers in …, 2020 - frontiersin.org
Events in fetal life impact long-term health outcomes. The placenta is the first organ to form
and is the site of juxtaposition between the maternal and fetal circulations. Most diseases of …

Development of the gut microbiota in infancy and its impact on health in later life

M Tanaka, J Nakayama - Allergology International, 2017 - jstage.jst.go.jp
abstract Gut microbial ecology and function are dynamic in infancy, but are stabilized in
childhood. The 'new friends' have a great impact on the development of the digestive tract …

[HTML][HTML] The immunobiology of preterm labor and birth: intra-amniotic inflammation or breakdown of maternal–fetal homeostasis

N Gomez-Lopez, J Galaz, D Miller… - …, 2022 - rep.bioscientifica.com
In brief The syndrome of preterm labor comprises multiple established and novel etiologies.
This review summarizes the distinct immune mechanisms implicated in preterm labor and …

Acute chorioamnionitis and funisitis: definition, pathologic features, and clinical significance

CJ Kim, R Romero, P Chaemsaithong… - American journal of …, 2015 - Elsevier
Acute inflammatory lesions of the placenta consist of diffuse infiltration of neutrophils at
different sites in the organ. These lesions include acute chorioamnionitis, funisitis, and …

Does the human placenta delivered at term have a microbiota? Results of cultivation, quantitative real-time PCR, 16S rRNA gene sequencing, and metagenomics

KR Theis, R Romero, AD Winters, JM Greenberg… - American journal of …, 2019 - Elsevier
Background The human placenta has been traditionally viewed as sterile, and microbial
invasion of this organ has been associated with adverse pregnancy outcomes. Yet, recent …

Microbial transmission, colonisation and succession: from pregnancy to infancy

L Xiao, F Zhao - Gut, 2023 - gut.bmj.com
The microbiome has been proven to be associated with many diseases and has been used
as a biomarker and target in disease prevention and intervention. Currently, the vital role of …

Periodontal disease and adverse pregnancy outcomes

YA Bobetsis, F Graziani, M Gürsoy… - Periodontology …, 2020 - Wiley Online Library
Periodontal diseases are considered not only to affect tooth‐supporting tissues but also to
have a cause‐and‐effect relationship with various systemic diseases and conditions, such …

Maternal health and the placental microbiome

E Pelzer, LF Gomez-Arango, HL Barrett, MD Nitert - Placenta, 2017 - Elsevier
Over the past decade, the role of the microbiome in regulating metabolism, immune function
and behavior in humans has become apparent. It has become clear that the placenta is not …