Pulmonary innate immune response determines the outcome of inflammation during pneumonia and sepsis-associated acute lung injury
V Kumar - Frontiers in immunology, 2020 - frontiersin.org
The lung is a primary organ for gas exchange in mammals that represents the largest
epithelial surface in direct contact with the external environment. It also serves as a crucial …
epithelial surface in direct contact with the external environment. It also serves as a crucial …
[HTML][HTML] Innate lymphoid cells: 10 years on
Innate lymphoid cells (ILCs) are lymphocytes that do not express the type of diversified
antigen receptors expressed on T cells and B cells. ILCs are largely tissue-resident cells and …
antigen receptors expressed on T cells and B cells. ILCs are largely tissue-resident cells and …
Cells of the human intestinal tract mapped across space and time
The cellular landscape of the human intestinal tract is dynamic throughout life, developing in
utero and changing in response to functional requirements and environmental exposures …
utero and changing in response to functional requirements and environmental exposures …
The roles of tertiary lymphoid structures in chronic diseases
Y Sato, K Silina, M van den Broek, K Hirahara… - Nature Reviews …, 2023 - nature.com
Tertiary lymphoid structures (TLSs) are ectopic lymphoid tissues that drive antigen-specific
immune responses at sites of chronic inflammation. Unlike secondary lymphoid organs such …
immune responses at sites of chronic inflammation. Unlike secondary lymphoid organs such …
Cellular and molecular mechanisms of allergic asthma
Asthma is a chronic disease of the airways, which affects more than 350 million people
worldwide. It is the most common chronic disease in children, affecting at least 30 million …
worldwide. It is the most common chronic disease in children, affecting at least 30 million …
Human immunology and immunotherapy: main achievements and challenges
J Varadé, S Magadán… - Cellular & Molecular …, 2021 - nature.com
The immune system is a fascinating world of cells, soluble factors, interacting cells, and
tissues, all of which are interconnected. The highly complex nature of the immune system …
tissues, all of which are interconnected. The highly complex nature of the immune system …
Role of inflammatory cells in airway remodeling in COPD
Y Wang, J Xu, Y Meng, IM Adcock… - International journal of …, 2018 - Taylor & Francis
COPD is characterized by chronic bronchitis, chronic airway obstruction, and emphysema,
leading to a progressive and irreversible decline in lung function. Inflammation is central for …
leading to a progressive and irreversible decline in lung function. Inflammation is central for …
Contribution to tumor angiogenesis from innate immune cells within the tumor microenvironment: implications for immunotherapy
The critical role of angiogenesis in promoting tumor growth and metastasis is strongly
established. However, tumors show considerable variation in angiogenic characteristics and …
established. However, tumors show considerable variation in angiogenic characteristics and …
Innate lymphoid cells in mucosal immunity
Innate lymphoid cells (ILCs) are innate counterparts of T cells that contribute to immune
responses by secreting effector cytokines and regulating the functions of other innate and …
responses by secreting effector cytokines and regulating the functions of other innate and …
[HTML][HTML] Tissue-specific features of innate lymphoid cells
I Meininger, A Carrasco, A Rao, T Soini, E Kokkinou… - Trends in …, 2020 - cell.com
Although the function of the circulating immune cell compartment has been studied in detail
for decades, limitations in terms of access and cell yields from peripheral tissues have …
for decades, limitations in terms of access and cell yields from peripheral tissues have …