MicroRNA-based diagnosis and therapy

PTB Ho, IM Clark, LTT Le - International journal of molecular sciences, 2022 - mdpi.com
MicroRNAs (miRNAs) are a group of endogenous non-coding RNAs that regulate gene
expression. Alteration in miRNA expression results in changes in the profile of genes …

miRNAs in lung cancer. A systematic review identifies predictive and prognostic miRNA candidates for precision medicine in lung cancer

S Zhong, H Golpon, P Zardo, J Borlak - Translational Research, 2021 - Elsevier
Lung cancer (LC) is the leading cause of cancer-related death worldwide and miRNAs play
a key role in LC development. To better diagnose LC and to predict drug treatment …

Epidemiology of lung cancer: Diagnosis and management of lung cancer: American College of Chest Physicians evidence-based clinical practice guidelines

AJ Alberg, MV Brock, JG Ford, JM Samet, SD Spivack - Chest, 2013 - Elsevier
Background Ever since a lung cancer epidemic emerged in the mid-1900s, the
epidemiology of lung cancer has been intensively investigated to characterize its causes …

Liquid biopsy for lung cancer: up-to-date and perspectives for screening programs

GMS Casagrande, MO Silva, RM Reis… - International Journal of …, 2023 - mdpi.com
Lung cancer is the deadliest cancer worldwide. Tissue biopsy is currently employed for the
diagnosis and molecular stratification of lung cancer. Liquid biopsy is a minimally invasive …

The role of exosomes and miRNAs in drug‐resistance of cancer cells

DH Bach, JY Hong, HJ Park… - International journal of …, 2017 - Wiley Online Library
Chemotherapy, one of the principal approaches for cancer patients, plays a crucial role in
controlling tumor progression. Clinically, tumors reveal a satisfactory response following the …

Circulating miRNAs: roles in cancer diagnosis, prognosis and therapy

G Cheng - Advanced drug delivery reviews, 2015 - Elsevier
MicroRNAs (miRNAs) belong to a class of small non-coding RNAs that regulate numerous
biological processes by targeting a broad set of messenger RNAs. Recently, miRNAs have …

Tumor‐derived exosomal lncRNA GAS5 as a biomarker for early‐stage non‐small‐cell lung cancer diagnosis

C Li, Y Lv, C Shao, C Chen, T Zhang… - Journal of cellular …, 2019 - Wiley Online Library
Diagnosis and treatment at an early stage may improve survival of non‐small‐cell lung
cancer (NSCLC). Previous studies have found that long noncoding RNA growth arrest …

A serum circulating miRNA diagnostic test to identify asymptomatic high‐risk individuals with early stage lung cancer

F Bianchi, F Nicassio, M Marzi, E Belloni… - EMBO molecular …, 2011 - embopress.org
Lung cancer is the first cause of cancer mortality worldwide, and its early detection is
currently the main available strategy to improve disease prognosis. While early diagnosis …

Hepatocellular carcinoma and microRNA: new perspectives on therapeutics and diagnostics

N Yang, NR Ekanem, CA Sakyi, SD Ray - Advanced drug delivery reviews, 2015 - Elsevier
Hepatocellular carcinoma (HCC) remains one of the most lethal forms of cancer in the world.
In this arena, utilities of microRNA (miRNA) as a sophisticated tool, in therapeutics and …

The role of liquid biopsy in early diagnosis of lung cancer

C Freitas, C Sousa, F Machado, M Serino… - Frontiers in …, 2021 - frontiersin.org
Liquid biopsy is an emerging technology with a potential role in the screening and early
detection of lung cancer. Several liquid biopsy-derived biomarkers have been identified and …