Alzheimer's disease (AD) is a progressive neurodegenerative disease that is the most
common cause of dementia. Symptoms of AD include memory loss, disorientation, mood …

Over the past decades, significant efforts have been made to understand the precise
mechanisms underlying the pathogenesis of Alzheimer's disease (AD), the most common …

Background: Poststroke cognitive impairments are common in stroke survivors, and pose a
high risk of incident dementia. However, the cause of these cognitive impairments is obscure …

Alzheimer disease (AD) is a leading cause of dementia that has gained prominence in our
aging society. Yet, the complexity of diagnosing AD and measuring its invasiveness poses …

In Alzheimer's disease and related dementias, amyloid beta (Aβ) and amyloid plaques can
disrupt long-term synaptic plasticity, learning and memory and cognitive function. Plaque …

Alzheimer's disease (AD) induces time-dependent changes in sphingolipid metabolism,
which may affect transcription regulation and neuronal phenotype. We, therefore, analyzed …

We have previously reported that the single transmembrane protein Dipeptidyl Peptidase
Like 6 (DPP6) impacts neuronal and synaptic development. DPP6-KO mice are impaired in …

Alzheimer's disease (AD) is a growing neurodegenerative disease without effective
treatments or therapies. Despite the use of different approaches and an extensive variety of …

In Alzheimer's disease (AD), decreases in the amount and synaptic localization of AMPA
receptors (AMPARs) result in weakened synaptic activity and dysfunction in synaptic …

Strong evidence indicates that amyloid beta (Aβ) inflicts its toxicity in Alzheimer's disease
(AD) by promoting uncontrolled elevation of cytosolic Ca2+ in neurons. We have previously …