Procalcitonin (PCT) and C-reactive protein (CRP) are commonly used biomarkers, but their
diagnostic advantage for neonatal early-onset (EOS) or late-onset (LOS) sepsis is …

Background A number of biomarkers have been studied for the diagnosis of sepsis in
paediatrics, but no gold standard has been identified. Procalcitonin (PCT) was demonstrated …

Neonatal sepsis is a major cause of morbidity and mortality. Early diagnosis and treatment of
the neonate with suspected sepsis are essential to prevent life-threatening complications …

Importance Rapid and accurate diagnosis of late-onset infection in newborn infants could
inform treatment decisions and avoid unnecessary administration of antibiotics. Objective To …

Neonatal sepsis is a bacterial bloodstream infection leading to severe clinical manifestations
frequently associated with death or irreversible long-term deficits. Antibiotics are the drug of …

BACKGROUND: The clinical signs of early-onset neonatal sepsis (EONS) are nonspecific
and indistinguishable from those of noninfectious disorders. The early diagnosis of EONS is …

OBJECTIVE: To evaluate the diagnostic and prognostic performance of inflammatory
markers for septic and non septic (localized) bacterial infections in patients with severe burn …

BACKGROUND: Late-onset sepsis (LOS) is among the leading causes of morbidity and
mortality in preterm newborns, and currently available diagnostic tools are inadequate. The …

Objective To investigate the accuracy of procalcitonin (PCT) as a diagnostic marker of
nosocomial sepsis (NS) and define the most accurate cut-off to distinguish infected from …

A meta-analysis was performed to assess the accuracy of the procalcitonin (PCT) test for
diagnosing neonatal sepsis. The major databases, MEDLINE, EMBASE and the Cochrane …