▪ Abstract The signal recognition particle (SRP) and its membrane-associated receptor (SR)
catalyze targeting of nascent secretory and membrane proteins to the protein translocation …

The synthesis of secretory or integral membrane proteins can be directly coupled to their
translocation across or insertion into membranes. In co-translational targeting, the …

Signal recognition particle (SRP) is an RNA and protein complex that exists in all domains of
life. It consists of one protein and one noncoding RNA in some bacteria. It is more complex …

The signal recognition particle (SRP) is a ribonucleoprotein particle essential for the
targeting of signal peptide-bearing proteins to the prokaryotic plasma membrane or the …

The signal recognition particle (SRP) and its membrane-bound receptor represent a
ubiquitous protein-targeting device utilized by organisms as different as bacteria and …

Signal sequences of secretory and membrane proteins are recognized by the signal
recognition particle (SRP) as they emerge from the ribosome. This results in their targeting to …

Targeting of ribosome–nascent chain complexes to the translocon in the endoplasmic
reticulum is mediated by the concerted action of the signal recognition particle (SRP) and …

Bacteria use several routes to target their exported proteins to the plasma membrane. The
majority are exported through pores formed by SecY and SecE. Two different molecular …

▪ Abstract The signal recognition particle (SRP) directs integral membrane and secretory
proteins to the cellular protein translocation machinery during translation. The SRP is an …

Cotranslational targeting directly couples synthesis of proteins to their translocation across
or insertion into membranes. The signal recognition particle (SRP) and its membrane-bound …