Epigenetics and lifestyle
JA Alegría-Torres, A Baccarelli, V Bollati - Epigenomics, 2011 - Taylor & Francis
The concept of 'lifestyle 'includes different factors such as nutrition, behavior, stress, physical
activity, working habits, smoking and alcohol consumption. Increasing evidence shows that …
activity, working habits, smoking and alcohol consumption. Increasing evidence shows that …
Multiple sclerosis: risk factors, prodromes, and potential causal pathways
Multiple sclerosis (MS) is a common, complex neurological disease. The precise aetiology of
MS is not yet known, although epidemiological data indicate that both genetic and …
MS is not yet known, although epidemiological data indicate that both genetic and …
Epigenetic transgenerational actions of environmental factors in disease etiology
MK Skinner, M Manikkam… - Trends in Endocrinology & …, 2010 - cell.com
The ability of environmental factors to promote a phenotype or disease state not only in the
individual exposed but also in subsequent progeny for successive generations is termed …
individual exposed but also in subsequent progeny for successive generations is termed …
Epigenetic mechanisms in neurological diseases: genes, syndromes, and therapies
RG Urdinguio, JV Sanchez-Mut, M Esteller - The Lancet Neurology, 2009 - thelancet.com
Epigenetic mechanisms such as DNA methylation and modifications to histone proteins
regulate high-order DNA structure and gene expression. Aberrant epigenetic mechanisms …
regulate high-order DNA structure and gene expression. Aberrant epigenetic mechanisms …
Environmental factors and their timing in adult-onset multiple sclerosis
Multiple sclerosis (MS) is a common, complex neurological disease. Epidemiological data
implicate both genetic and environmental factors in the etiology of MS, with various factors …
implicate both genetic and environmental factors in the etiology of MS, with various factors …
Epigenetics: molecular mechanisms and implications for disease
Epigenetics is rising to prominence in biology as a mechanism by which environmental
factors have intermediate-term effects on gene expression without changing the underlying …
factors have intermediate-term effects on gene expression without changing the underlying …
Epidemiology of multiple sclerosis
SV Ramagopalan, AD Sadovnick - Neurologic clinics, 2011 - neurologic.theclinics.com
Multiple sclerosis (MS) is the most common disease of the central nervous system that
causes permanent disability in young adults. 1 Based on strong circumstantial evidence, MS …
causes permanent disability in young adults. 1 Based on strong circumstantial evidence, MS …
The increasing incidence and prevalence of female multiple sclerosis—a critical analysis of potential environmental factors
Multiple sclerosis (MS) is the most common acquired inflammatory demyelinating disorder of
the central nervous system (CNS). Not unlike many inflammatory diseases with a presumed …
the central nervous system (CNS). Not unlike many inflammatory diseases with a presumed …
Is hypovitaminosis D one of the environmental risk factors for multiple sclerosis?
C Pierrot-Deseilligny, JC Souberbielle - Brain, 2010 - academic.oup.com
The role of hypovitaminosis D as a possible risk factor for multiple sclerosis is reviewed.
First, it is emphasized that hypovitaminosis D could be only one of the risk factors for multiple …
First, it is emphasized that hypovitaminosis D could be only one of the risk factors for multiple …
The epigenetics of autoimmunity
The etiology of autoimmune diseases remains largely unknown. Concordance rates in
monozygotic twins are lower than 50% while genome-wide association studies propose …
monozygotic twins are lower than 50% while genome-wide association studies propose …