Epilepsy in adults
Epilepsy is one of the most common serious brain conditions, affecting over 70 million
people worldwide. Its incidence has a bimodal distribution with the highest risk in infants and …
people worldwide. Its incidence has a bimodal distribution with the highest risk in infants and …
Recommendations for the use of structural magnetic resonance imaging in the care of patients with epilepsy: a consensus report from the International League Against …
Structural magnetic resonance imaging (MRI) is of fundamental importance to the diagnosis
and treatment of epilepsy, particularly when surgery is being considered. Despite previous …
and treatment of epilepsy, particularly when surgery is being considered. Despite previous …
The ILAE consensus classification of focal cortical dysplasia: an update proposed by an ad hoc task force of the ILAE diagnostic methods commission
Ongoing challenges in diagnosing focal cortical dysplasia (FCD) mandate continuous
research and consensus agreement to improve disease definition and classification. An …
research and consensus agreement to improve disease definition and classification. An …
Seizure outcome and use of antiepileptic drugs after epilepsy surgery according to histopathological diagnosis: a retrospective multicentre cohort study
Background Surgery is a widely accepted treatment option for drug-resistant focal epilepsy.
A detailed analysis of longitudinal postoperative seizure outcomes and use of antiepileptic …
A detailed analysis of longitudinal postoperative seizure outcomes and use of antiepileptic …
Timing of referral to evaluate for epilepsy surgery: Expert Consensus Recommendations from the Surgical Therapies Commission of the International League Against …
Epilepsy surgery is the treatment of choice for patients with drug‐resistant seizures. A timely
evaluation for surgical candidacy can be life‐saving for patients who are identified as …
evaluation for surgical candidacy can be life‐saving for patients who are identified as …
[HTML][HTML] NODDI in clinical research
Diffusion MRI (dMRI) has proven to be a useful imaging approach for both clinical diagnosis
and research investigating the microstructures of nervous tissues, and it has helped us to …
and research investigating the microstructures of nervous tissues, and it has helped us to …
Dissecting the genetic basis of focal cortical dysplasia: a large cohort study
Genetic malformations of cortical development (MCDs), such as mild MCDs (mMCD), focal
cortical dysplasia (FCD), and hemimegalencephaly (HME), are major causes of severe …
cortical dysplasia (FCD), and hemimegalencephaly (HME), are major causes of severe …
Structural brain abnormalities in the common epilepsies assessed in a worldwide ENIGMA study
Progressive functional decline in the epilepsies is largely unexplained. We formed the
ENIGMA-Epilepsy consortium to understand factors that influence brain measures in …
ENIGMA-Epilepsy consortium to understand factors that influence brain measures in …
Adult epilepsy
AA Asadi-Pooya, F Brigo, S Lattanzi, I Blumcke - The Lancet, 2023 - thelancet.com
Epilepsy is a common medical condition that affects people of all ages, races, social classes,
and geographical regions. Diagnosis of epilepsy remains clinical, and ancillary …
and geographical regions. Diagnosis of epilepsy remains clinical, and ancillary …
Somatic mutations activating the mTOR pathway in dorsal telencephalic progenitors cause a continuum of cortical dysplasias
Focal cortical dysplasia (FCD) and hemimegalencephaly (HME) are epileptogenic
neurodevelopmental malformations caused by mutations in mTOR pathway genes. Deep …
neurodevelopmental malformations caused by mutations in mTOR pathway genes. Deep …