Silk biomaterials in wound healing and skin regeneration therapeutics: From bench to bedside

D Chouhan, BB Mandal - Acta biomaterialia, 2020 - Elsevier
Silk biomaterials are known for biomedical and tissue engineering applications including
drug delivery and implantable devices owing to their biocompatible and a wide range of …

Silk protein-based hydrogels: Promising advanced materials for biomedical applications

S Kapoor, SC Kundu - Acta biomaterialia, 2016 - Elsevier
Hydrogels are a class of advanced material forms that closely mimic properties of the soft
biological tissues. Several polymers have been explored for preparing hydrogels with …

Silk-based biomaterials for sustained drug delivery

T Yucel, ML Lovett, DL Kaplan - Journal of Controlled Release, 2014 - Elsevier
Silk presents a rare combination of desirable properties for sustained drug delivery,
including aqueous-based purification and processing options without chemical cross …

Silk fibroin as a vehicle for drug delivery applications

E Wenk, HP Merkle, L Meinel - Journal of controlled release, 2011 - Elsevier
Silk fibroin (SF), a naturally occurring protein polymer, has several unique properties making
it a favorable matrix for the incorporation and delivery of a range of therapeutic agents. SF is …

Silk fibroin as a functional biomaterial for drug and gene delivery

MA Tomeh, R Hadianamrei, X Zhao - Pharmaceutics, 2019 - mdpi.com
Silk is a natural polymer with unique physicochemical and mechanical properties which
makes it a desirable biomaterial for biomedical and pharmaceutical applications. Silk fibroin …

Temperature-responsive compounds as in situ gelling biomedical materials

HJ Moon, MH Park, MK Joo, B Jeong - Chemical Society Reviews, 2012 - pubs.rsc.org
Aqueous solutions that undergo sol-to-gel transition as the temperature increases have
been extensively studied during the last decade. The material can be designed by …

Smart self‐assembled hybrid hydrogel biomaterials

J Kopeček, J Yang - Angewandte Chemie International Edition, 2012 - Wiley Online Library
Hybrid biomaterials are systems created from components of at least two distinct classes of
molecules, for example, synthetic macromolecules and proteins or peptide domains. The …

Elastin-based materials

JF Almine, DV Bax, SM Mithieux… - Chemical Society …, 2010 - pubs.rsc.org
Elastin is a versatile elastic protein that dominates flexible tissues capable of recoil, and
facilitates commensurate cell interactions in these tissues in all higher vertebrates. Elastin's …

Natural and synthetic polymers as drug carriers for delivery of therapeutic proteins

MS Hamid Akash, K Rehman, S Chen - Polymer Reviews, 2015 - Taylor & Francis
In order to cure and treat health-related disorders, therapeutic substance must reach its
target site with a constant concentration over a long period of time. As oral administration is …

Silk-elastin-like protein biomaterials for the controlled delivery of therapeutics

W Huang, A Rollett, DL Kaplan - Expert opinion on drug delivery, 2015 - Taylor & Francis
Introduction: Genetically engineered biomaterials are useful for controlled delivery owing to
their rational design, tunable structure–function, biocompatibility, degradability and target …