Given that hypoxia is a persistent physiological feature of many different solid tumors and a
key driver for cancer malignancy, it is thought to be a major target in cancer treatment …

Angiogenesis is the process through which novel blood vessels are formed from pre-existing
ones and it is involved in both physiological and pathological processes of the body …

Self-assembled peptides and proteins possess tremendous potential as targeted drug
delivery systems and key applications of these well-defined nanostructures reside in anti …

Resistance to cancer therapy is a major barrier to cancer management. Conventional views
have proposed that acquisition of resistance may result from genetic mutations. However …

Simple Summary Tumors are not masses of cancer cells alone but made up of cancer cells,
other cells including fibroblasts, macrophages, endothelial cells, as well as secreted factors …

Immune checkpoint blockage has been considered a breakthrough in cancer treatment,
achieving encouraging anti-tumor effects in some advanced solid malignancies. However …

Incapacitated immune system is a characteristic hallmark of solid tumors. Immune system
within a tumor undergoes an imbalance in cellular dispersion and functionality. Effector cells …

Cancer cells resistance to various therapies remains to be a key challenge nowadays. For a
long time, scientists focused on tumor cells themselves for the mechanisms of acquired drug …

Extracellular heat shock proteins (ex-HSPs) have been found in exosomes, oncosomes,
membrane surfaces, as well as free HSP in cancer and various pathological conditions, also …

Angiogenesis is involved in physiological and pathological processes in the body. Tumor
angiogenesis is a key factor associated with tumor growth, progression, and metastasis …