Dopamine, immunity, and disease

B Channer, SM Matt, EA Nickoloff-Bybel, V Pappa… - Pharmacological …, 2023 - Elsevier
The neurotransmitter dopamine is a key factor in central nervous system (CNS) function,
regulating many processes including reward, movement, and cognition. Dopamine also …

ADHD: Reviewing the causes and evaluating solutions

L Núñez-Jaramillo, A Herrera-Solís… - Journal of personalized …, 2021 - mdpi.com
Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder in which
patients present inattention, hyperactivity, and impulsivity. The etiology of this condition is …

Review of rodent models of attention deficit hyperactivity disorder

SL Regan, MT Williams, CV Vorhees - Neuroscience & Biobehavioral …, 2022 - Elsevier
Attention deficit hyperactivity disorder (ADHD) is a polygenic neurodevelopmental disorder
that affects 8–12% of children and> 4% of adults. Environmental factors are believed to …

Attention-deficit/hyperactive disorder updates

M Kessi, H Duan, J Xiong, B Chen, F He… - Frontiers in molecular …, 2022 - frontiersin.org
Background Attention-deficit/hyperactive disorder (ADHD) is a neurodevelopmental disorder
that commonly occurs in children with a prevalence ranging from 3.4 to 7.2%. It profoundly …

Retinal electrophysiology in central nervous system disorders. A review of human and mouse studies

PA Constable, JKH Lim, DA Thompson - Frontiers in Neuroscience, 2023 - frontiersin.org
The retina and brain share similar neurochemistry and neurodevelopmental origins, with the
retina, often viewed as a “window to the brain.” With retinal measures of structure and …

Behavioral phenotyping of dopamine transporter knockout rats: compulsive traits, motor stereotypies, and anhedonia

S Cinque, F Zoratto, A Poleggi, D Leo… - Frontiers in …, 2018 - frontiersin.org
Alterations in dopamine neurotransmission are generally associated with diseases such as
attention-deficit/hyperactivity disorder (ADHD) and obsessive-compulsive disorder (OCD) …

The development of the mesoprefrontal dopaminergic system in health and disease

KUS Islam, N Meli, S Blaess - Frontiers in Neural Circuits, 2021 - frontiersin.org
Midbrain dopaminergic neurons located in the substantia nigra and the ventral tegmental
area are the main source of dopamine in the brain. They send out projections to a variety of …

Rodent models of attention-deficit hyperactivity disorder: An updated framework for model validation and therapeutic drug discovery

KM Kantak - Pharmacology Biochemistry and Behavior, 2022 - Elsevier
There are over twenty rodent models of Attention-Deficit Hyperactivity Disorder (ADHD), with
most reflecting a recognized ADHD subtype. Of these, only five rat models (Neonatal 6 …

The Homer1 family of proteins at the crossroad of dopamine-glutamate signaling: An emerging molecular “Lego” in the pathophysiology of psychiatric disorders. A …

A de Bartolomeis, A Barone, EF Buonaguro… - Neuroscience & …, 2022 - Elsevier
Once considered only scaffolding proteins at glutamatergic postsynaptic density (PSD),
Homer1 proteins are increasingly emerging as multimodal adaptors that integrate different …

Canonical and non-canonical antipsychotics' dopamine-related mechanisms of present and next generation molecules: a systematic review on translational highlights …

A de Bartolomeis, M Ciccarelli, G De Simone… - International Journal of …, 2023 - mdpi.com
Schizophrenia is a severe psychiatric illness affecting almost 25 million people worldwide
and is conceptualized as a disorder of synaptic plasticity and brain connectivity …