Pathogenesis of Aspergillus fumigatus in Invasive Aspergillosis

TRT Dagenais, NP Keller - Clinical microbiology reviews, 2009 - Am Soc Microbiol
Aspergillus species are globally ubiquitous saprophytes found in a variety of ecological
niches. Almost 200 species of aspergilli have been identified, less than 20 of which are …

Gliotoxin–bane or boon?

DH Scharf, AA Brakhage… - Environmental …, 2016 - Wiley Online Library
Gliotoxin (GT) is the most important epidithiodioxopiperazine (ETP)‐type fungal toxin. GT
was originally isolated from T richoderma species as an antibiotic substance involved in …

Aspergillus‐Associated Airway Disease, Inflammation, and the Innate Immune Response

SH Chotirmall, M Al-Alawi, B Mirkovic… - BioMed research …, 2013 - Wiley Online Library
Aspergillus moulds exist ubiquitously as spores that are inhaled in large numbers daily.
Whilst most are removed by anatomical barriers, disease may occur in certain …

Crossover fungal pathogens: the biology and pathogenesis of fungi capable of crossing kingdoms to infect plants and humans

GM Gauthier, NP Keller - Fungal genetics and biology, 2013 - Elsevier
The outbreak of fungal meningitis associated with contaminated methylprednisolone acetate
has thrust the importance of fungal infections into the public consciousness. The …

In vitro models for studying respiratory host–pathogen interactions

SL Barron, J Saez, RM Owens - Advanced Biology, 2021 - Wiley Online Library
Respiratory diseases and lower respiratory tract infections are among the leading cause of
death worldwide and, especially given the recent severe acute respiratory syndrome …

Aspergillus fumigatus CalA binds to integrin α5β1 and mediates host cell invasion

H Liu, MJ Lee, NV Solis, QT Phan, M Swidergall… - Nature …, 2016 - nature.com
Aspergillus fumigatus is an opportunistic fungal pathogen that invades pulmonary epithelial
cells and vascular endothelial cells by inducing its own endocytosis, but the mechanism by …

Molecular mechanism of Aspergillus fumigatus adherence to host constituents

DC Sheppard - Current opinion in microbiology, 2011 - Elsevier
Inhaled conidia of Aspergillus fumigatus rapidly adhere to pulmonary epithelial cells and
other host constituents. Identifying molecular mechanisms underlying A. fumigatus …

[图书][B] Animal lectins: form, function and clinical applications

GS Gupta - 2012 - books.google.com
Animal Lectins: Form, Function and Clinical Applications presents up-to-date knowledge of
animal lectins. Detailed descriptions on biological activities, tissue and/or subcellular …

Host cell invasion by medically important fungi

DC Sheppard, SG Filler - Cold Spring …, 2015 - perspectivesinmedicine.cshlp.org
To infect the host and cause disease, many medically important fungi invade normally
nonphagocytic host cells, such as endothelial cells and epithelial cells. Host cell invasion is …

Pathogen interactions with endothelial cells and the induction of innate and adaptive immunity

C Konradt, CA Hunter - European journal of immunology, 2018 - Wiley Online Library
There are over 10 trillion endothelial cells (EC) that line the vasculature of the human body.
These cells not only have specialized functions in the maintenance of homeostasis within …