Pathophysiology of mesangial expansion in diabetic nephropathy: mesangial structure, glomerular biomechanics, and biochemical signaling and regulation

HY Thomas, AN Ford Versypt - Journal of Biological Engineering, 2022 - Springer
Diabetic nephropathy, a kidney complication arising from diabetes, is the leading cause of
death in diabetic patients. Unabated, the growing epidemic of diabetes is increasing …

Paracrine regulation of the renal microcirculation

LG Navar, EW Inscho, SA Majid, JD Imig… - Physiological …, 1996 - journals.physiology.org
There has been an explosive growth of interest in the multiple interacting paracrine systems
that influence renal microvascular function. This review first discusses the membrane …

In situ hybridization evidence for angiotensinogen messenger RNA in the rat proximal tubule. An hypothesis for the intrarenal renin angiotensin system.

JR Ingelfinger, WM Zuo, EA Fon… - The Journal of …, 1990 - Am Soc Clin Investig
We examined angiotensinogen gene expression in rat kidney by in situ hybridization
histochemistry. Using a rat cRNA probe to angiotensinogen, we demonstrated …

pH regulation in single glomerular mesangial cells. I. Acid extrusion in absence and presence of HCO3

G Boyarsky, MB Ganz, RB Sterzel… - American Journal of …, 1988 - journals.physiology.org
We have developed a technique to measure the fluorescence of a pH-sensitive dye (2, 7-
biscarboxyethyl-5 (6)-carboxyfluorescein) in single glomerular mesangial cells in culture …

Effect of water intake on the progression of chronic renal failure in the 5/6 nephrectomized rat

N Bouby, S Bachmann, D Bichet… - American Journal of …, 1990 - journals.physiology.org
This study tests the possible influence of the urinary concentrating process and/or of
vasopressin (AVP) on the progression of early chronic renal failure (CRF). Male Sprague …

In situ hybridization studies of prostacyclin receptor mRNA expression in various mouse organs

H Oida, T Namba, Y Sugimoto… - British journal of …, 1995 - Wiley Online Library
1 Expression of prostacyclin receptor (IP receptor) mRNA was examined in various mouse
organs, and the cells expressing IP receptor mRNA were identified by in situ hybridization …

Hemodynamic basis for glomerular injury in rats with desoxycorticosterone-salt hypertension.

LD Dworkin, TH Hostetter, HG Rennke… - The Journal of …, 1984 - Am Soc Clin Investig
Micropuncture and/or morphologic studies were performed in seven groups of
uninephrectomized (UNX) adult male Munich-Wistar rats. Control groups 1, 3, and 6 …

Sex differences in renal hemodynamics in rats

K Munger, C Baylis - American Journal of Physiology-Renal …, 1988 - journals.physiology.org
These studies were designed to investigate sex differences in renal hemodynamics under
control conditions and in response to two different cyclooxygenase inhibitors. Studies were …

[HTML][HTML] Short-term effects of tolvaptan on renal function and volume in patients with autosomal dominant polycystic kidney disease

MV Irazabal, VE Torres, MC Hogan, J Glockner… - Kidney international, 2011 - Elsevier
Tolvaptan and related V 2-specific vasopressin receptor antagonists have been shown to
delay disease progression in animal models of polycystic kidney disease. Slight elevations …

[HTML][HTML] Brenner and Rector's the kidney

PH Nachman, JC Jennette, RJ Falk - 2012 - doctorlib.info
The underlying cause of most glomerular diseases remains an enigma. Infectious agents,
autoimmunity, drugs, inherited disorders, and environmental agents have been implicated …