It is well known that breathing introduces rhythmical oscillations in the heart rate and arterial
pressure levels. Sympathetic oscillations coupled to the respiratory activity have been …

The ongoing process of breathing underlies the gas exchange essential for mammalian life.
Each respiratory cycle ensues from the activity of rhythmic neural circuits in the brainstem …

The analgesic utility of opioid-based drugs is limited by the life-threatening risk of respiratory
depression. Opioid-induced respiratory depression (OIRD), mediated by the μ-opioid …

The circuit organization within the mammalian brainstem respiratory network, specifically
within and between the pre-Bötzinger (pre-BötC) and Bötzinger (BötC) complexes, and the …

Key points In addition to reductions in respiratory rate, opioids also cause aspiration and
difficulty swallowing, indicating impairment of the upper airways. The Kölliker–Fuse (KF) …

Now with videos! Dysphagia Following Stroke, Third Edition is a practical and easy-to-use
resource for clinicians treating swallowing disorders in the stroke population. The authors …

Overdoses caused by the opioid agonist fentanyl have increased exponentially in recent
years. Identifying mechanisms to counter progression to fatal respiratory apnea during …

Opioid-induced respiratory depression (OIRD) is the major cause of death associated with
opioid analgesics and drugs of abuse, but the underlying cellular and molecular …

Chronic pain is one of the most common reasons adults seek medical care and is often
managed with opioid analgesics; however, opioids may cause respiratory depression by …

Breathing is a vital process providing the exchange of gases between the lungs and
atmosphere. During quiet breathing, pumping air from the lungs is mostly performed by …