The pathobiology of mucositis

ST Sonis - Nature Reviews Cancer, 2004 - nature.com
Oral and gastrointestinal mucositis is a toxicity of many forms of radiotherapy and
chemotherapy. It has a significant impact on health, quality of life and economic outcomes …

Mucositis as a biological process: a new hypothesis for the development of chemotherapy-induced stomatotoxicity

ST Sonis - Oral oncology, 1998 - Elsevier
Mucositis induced by antineoplastic drugs is an important, dose-limiting and costly side
effect of cancer therapy. The ulcerative lesions which result are frequent systemic portals of …

Palifermin for oral mucositis after intensive therapy for hematologic cancers

R Spielberger, P Stiff, W Bensinger… - … England Journal of …, 2004 - Mass Medical Soc
Background Oral mucositis is a complication of intensive chemotherapy and radiotherapy
with no effective treatment. We tested the ability of palifermin (recombinant human …

Effect of prophylactic low level laser therapy on oral mucositis: a systematic review and meta-analysis

S Oberoi, G Zamperlini–Netto, J Beyene, NS Treister… - PLoS one, 2014 - journals.plos.org
Background Objective was to determine whether prophylactic low level laser therapy (LLLT)
reduces the risk of severe mucositis as compared to placebo or no therapy. Methods …

Oral mucositis complicating chemotherapy and/or radiotherapy: options for prevention and treatment

WJ Köstler, M Hejna, C Wenzel… - CA: a cancer journal for …, 2001 - Wiley Online Library
Chemotherapy‐and radiotherapy‐induced oral mucositis represents a therapeutic challenge
frequently encountered in cancer patients. This side effect causes significant morbidity and …

Patient reports of complications of bone marrow transplantation

LA Bellm, JB Epstein, A Rose-Ped, P Martin… - Supportive care in …, 2000 - Springer
In recent years, significant improvements have been made in the management of
neutropenia and thrombocytopenia and other potentially life-threatening complications of …

Mucositis: its occurrence, consequences, and treatment in the oncology setting

JL Pico, A Avila-Garavito, P Naccache - The oncologist, 1998 - academic.oup.com
Mucositis induced by antineoplastic drugs is an important, dose-limiting, and costly side
effect of cancer therapy. The ulcerative lesions produced by mucotoxic chemoradiotherapy …

Oral mucositis

ST Sonis - Anti-cancer drugs, 2011 - journals.lww.com
Oral mucositis remains one of the most common and troubling side effects of standard
chemoradiation regimens used for the treatment of head and neck cancer. Virtually all …

Risk factors for ulcerative oral mucositis in cancer patients: unanswered questions

A Barasch, DE Peterson - Oral oncology, 2003 - Elsevier
A multitude of laboratory and clinical research studies of ulcerative oral mucositis induced by
cytotoxic cancer therapies have been reported during the past decade. However, a …

NCCN task force report: prevention and management of mucositis in cancer care

W Bensinger, M Schubert, KK Ang, D Brizel… - Journal of the National …, 2008 - jnccn.org
Oral mucositis (OM) has emerged as a common cause of dose delays and interruptions of
cancer therapies such as multicycle chemotherapy, myeloablative chemotherapy, and …