Spontaneous and sensory-evoked activity propagates across varying spatial scales in the
mammalian cortex, but technical challenges have limited conceptual links between the …

Calcium imaging is commonly used to visualize neural activity in vivo. In particular,
mesoscale calcium imaging provides large fields of view, allowing for the simultaneous …

Whereas sensory perception relies on specialized sensory pathways, it is unclear whether
these pathways originate as modality-specific circuits. We demonstrated that somatosensory …

Visual spatial perception in the mammalian brain occurs through two parallel pathways: one
reaches the primary visual cortex (V1) through the thalamus and another the superior …

Even in the absence of external stimuli, the brain remains remarkably active, with neurons
continuously firing and communicating with each other. It is not merely random firing of …

Monitoring the hypnotic component of anesthesia during surgeries is critical to prevent
intraoperative awareness and reduce adverse side effects. For this purpose …

During early development, before the eyes open, synaptic refinement of sensory networks
depends on activity generated by developing neurons themselves. In the mouse visual …

In mammals with binocular vision, integration of the left and right visual scene relies on
information in the center visual field, which are relayed from each retina in parallel and …

Demixing signals in transcranial videos of neuronal calcium flux across the cerebral
hemispheres is a key step before mapping features of cortical organization. Here we …

Spontaneous network activity shapes emerging neuronal circuits during early brain
development prior to sensory perception. However, how neuromodulation influences this …