Dictyostelium: An Important Source of Structural and Functional Diversity in Drug Discovery
Y Kubohara, H Kikuchi - Cells, 2018 - mdpi.com
The cellular slime mold Dictyostelium discoideum is an excellent model organism for the
study of cell and developmental biology because of its simple life cycle and ease of use …
study of cell and developmental biology because of its simple life cycle and ease of use …
The Dictyostelium model for mitochondrial biology and disease
XG Pearce, SJ Annesley, PR Fisher - The International Journal of …, 2019 - ijdb.ehu.es
The unicellular slime mould Dictyostelium discoideum is a valuable eukaryotic model
organism in the study of mitochondrial biology and disease. As a member of the …
organism in the study of mitochondrial biology and disease. As a member of the …
Pharmacological Evidence That Dictyostelium Differentiation-Inducing Factor 1 Promotes Glucose Uptake Partly via an Increase in Intracellular cAMP Content in …
Y Kubohara, Y Fukunaga, H Kikuchi, H Kuwayama - Molecules, 2023 - mdpi.com
Differentiation-inducing factor 1 (DIF-1) isolated from the cellular slime mold Dictyostelium
discoideum can inhibit mammalian calmodulin-dependent cAMP/cGMP phosphodiesterase …
discoideum can inhibit mammalian calmodulin-dependent cAMP/cGMP phosphodiesterase …
Differentiation-inducing factor 1 activates cofilin through pyridoxal phosphatase and AMP-activated protein kinase, resulting in mitochondrial fission
T Inoue, K Miura, R Han, F Seto-Tetsuo… - Journal of …, 2023 - Elsevier
Abstract Differentiation-inducing factor 1 (DIF-1) is a morphogen produced by Dictyostelium
discoideum that inhibits the proliferation and migration of both D. discoideum and most …
discoideum that inhibits the proliferation and migration of both D. discoideum and most …
Derivatives of Differentiation-Inducing Factor 1 Differentially Control Chemotaxis and Stalk Cell Differentiation in Dictyostelium discoideum
H Kuwayama, H Kikuchi, Y Kubohara - Biology, 2023 - mdpi.com
Simple Summary In this study, we examined the effects of nine DIF derivatives on
chemotactic cell movement toward cAMP and compared their chemotaxis-modulating …
chemotactic cell movement toward cAMP and compared their chemotaxis-modulating …
In Vivo Assembly of a Dictyostelium Lamin Mutant Induced by Light, Mechanical Stress, and pH
M Grafe, P Hofmann, P Batsios, I Meyer, R Gräf - Cells, 2020 - mdpi.com
We expressed Dictyostelium lamin (NE81) lacking both a functional nuclear localization
signal and a CAAX-box for C-terminal lipid modification. This lamin mutant assembled into …
signal and a CAAX-box for C-terminal lipid modification. This lamin mutant assembled into …
[PDF][PDF] THE DICTYOSTELIUM DISCOIDEUM DIPKS14: A MEMBRANE-ANCHORED HIGHLY REDUCING ITERATIVE POLYKETIDE SYNTHASE SIMILAR TO ONES …
L MUTHUKUMAR… - Asian Jr. of Microbiol …, 2020 - envirobiotechjournals.com
Naturally occurring iterative type I polyketide synthase enzymes are known to make
therapeutic polyketide molecules that act against bacteria, cancer and cholesterol …
therapeutic polyketide molecules that act against bacteria, cancer and cholesterol …