Molecular genetics of infertility: loss-of-function mutations in humans and corresponding knockout/mutated mice

SY Jiao, YH Yang, SR Chen - Human reproduction update, 2021 - academic.oup.com
BACKGROUND Infertility is a major issue in human reproductive health, affecting an
estimated 15% of couples worldwide. Infertility can result from disorders of sex development …

A multi-faceted approach to understanding male infertility: gene mutations, molecular defects and assisted reproductive techniques (ART)

E Tahmasbpour, D Balasubramanian… - Journal of assisted …, 2014 - Springer
Background The assisted reproductive techniques aimed to assist infertile couples have
their own offspring carry significant risks of passing on molecular defects to next …

A combinatorial F box protein directed pathway controls TRAF adaptor stability to regulate inflammation

BB Chen, TA Coon, JR Glasser, BJ McVerry… - Nature …, 2013 - nature.com
Uncontrolled activation of tumor necrosis factor receptor–associated factor (TRAF) proteins
may result in profound tissue injury by linking surface signals to cytokine release. Here we …

Ubiquitin-proteasome system–regulated protein degradation in spermatogenesis

Y Xiong, C Yu, Q Zhang - Cells, 2022 - mdpi.com
Spermatogenesis is a prolonged and highly ordered physiological process that produces
haploid male germ cells through more than 40 steps and experiences dramatic …

Ubiquitin–proteasome system in spermatogenesis

R Bose, G Manku, M Culty, SS Wing - … protein modifications in the …, 2014 - Springer
Spermatogenesis represents a complex succession of cell division and differentiation events
resulting in the continuous formation of spermatozoa. Such a complex program requires …

Di-n-butyl phthalate (DBP) exposure induces oxidative damage in testes of adult rats

D Zhou, H Wang, J Zhang, X Gao, W Zhao… - Systems Biology in …, 2010 - Taylor & Francis
Di-n-butyl phthalate (DBP) is a ubiquitous environmental pollutant, extensively used as a
plasticizer in many products including plastics, cosmetics, and medical devices. Some …

Fertility‐associated metabolites in bull seminal plasma and blood serum: 1H nuclear magnetic resonance analysis

A Kumar, T Kroetsch, P Blondin… - Molecular Reproduction …, 2015 - Wiley Online Library
Early estimation of bull fertility is highly desirable for the conservation of male genetics of
endangered species and for the exploitation of genetically superior sires in artificial …

[HTML][HTML] Effects of DHA-enriched hen egg yolk and L-cysteine supplementation on quality of cryopreserved boar semen

P Chanapiwat, K Kaeoket… - Asian journal of andrology, 2009 - ncbi.nlm.nih.gov
The objective of the present study was to determine the effects of docosahexaenoic acid
(DHA)-enriched hen egg yolks and L-cysteine supplementation on the qualities of the …

[PDF][PDF] Infertility in male; risk factors, causes and management-A review

WE Olooto - J Microbiol Biotechnol Res, 2012 - androcryos.co.za
The etiology and psychosocial burden of infertility amongst couples especially in Africans
has been stressed by various researchers. Male factors have been discovered to account for …

[HTML][HTML] Potential pathways of pesticide action on erectile function–a contributory factor in male infertility

RP Kaur, V Gupta, AF Christopher, P Bansal - Asian Pacific Journal of …, 2015 - Elsevier
One of the important objectives of this manuscript is to focus on the place of erectile
dysfunction as an important factor for infertility. The review is about correlating the …