The gold drugs, gold sodium thiomalate (Myocrisin), aurothioglucose (Solganal), and the
orally administered auranofin (Ridaura), are utilized in modern medicine for the treatment of …

Auranofin (AUR) is an orally available lipophilic gold-based anti-inflammatory compound
used for the treatment of rheumatoid arthritis (RA). Recent evidence indicates that AUR may …

Bacterial biofilms are complex and highly antibiotic-resistant aggregates of microbes that
form on surfaces in the environment and body including medical devices. They are key …

Immunodepression, whether due to HIV infection or organ transplantation, has increased
human vulnerability to fungal infections. These conditions have created an optimal …

Antimicrobial resistance is considered one of the three most important health problems by
the World Health Organization. The emergence and spread of an increasing number of …

A majority of microbial infections are associated with biofilms. Targeting biofilms is
considered an effective strategy to limit microbial virulence while minimizing the …

Introduction Antimicrobial resistance is a pressing global concern that has led to the search
for new antibacterial agents with novel targets or non-traditional approaches. Recently …

The misuse of antimicrobials has caused a remarkable increase of antibiotic-resistant
bacteria. Developing novel antimicrobial agents with high activity and low rates of resistance …

As increasing numbers of colistin-resistant bacteria emerge, new therapies are urgently
needed to treat infections caused by these pathogens. The discovery of new combination …

Colistin-resistant (Col-R) bacteria are steadily increasing, and are extremely difficult to treat.
New drugs or therapies are urgently needed to treat infections caused by these pathogens …