Risk factors for non-motor symptoms in Parkinson's disease

J Marinus, K Zhu, C Marras, D Aarsland… - The Lancet …, 2018 - thelancet.com
Non-motor symptoms (NMS) of Parkinson's disease can be predominant as the disease
advances, thereby constituting a major source of disease burden for patients and caregivers …

A systematic review of the literature on disorders of sleep and wakefulness in Parkinson's disease from 2005 to 2015

LM Chahine, AW Amara, A Videnovic - Sleep medicine reviews, 2017 - Elsevier
Sleep disorders are among the most common non-motor manifestations in Parkinson's
disease (PD) and have a significant negative impact on quality of life. While sleep disorders …

Pimavanserin for patients with Parkinson's disease psychosis: a randomised, placebo-controlled phase 3 trial

J Cummings, S Isaacson, R Mills, H Williams… - The Lancet, 2014 - thelancet.com
Background Parkinson's disease psychosis, which includes hallucinations and delusions, is
frequent and debilitating in people with Parkinson's disease. We aimed to assess safety and …

Non-motor symptoms of Parkinson's disease: diagnosis and management

KR Chaudhuri, DG Healy, AHV Schapira - The Lancet Neurology, 2006 - thelancet.com
The clinical diagnosis of Parkinson's disease rests on the identification of the characteristics
related to dopamine deficiency that are a consequence of degeneration of the substantia …

The metric properties of a novel non‐motor symptoms scale for Parkinson's disease: results from an international pilot study

KR Chaudhuri, P Martinez‐Martin… - Movement …, 2007 - Wiley Online Library
Non‐motor symptoms (NMS) in Parkinson's disease (PD) are common, significantly reduce
quality of life and at present there is no validated clinical tool to assess the progress or …

What are the most important nonmotor symptoms in patients with Parkinson's disease and are we missing them?

DA Gallagher, AJ Lees, A Schrag - Movement Disorders, 2010 - Wiley Online Library
Nonmotor symptoms (NMS) are increasingly recognized as important and neglected aspects
of Parkinson's disease (PD). We evaluated their relative frequency and comparative impact …

Assessment of autonomic dysfunction in Parkinson's disease: the SCOPA‐AUT

M Visser, J Marinus, AM Stiggelbout… - … : official journal of the …, 2004 - Wiley Online Library
We developed a questionnaire to assess autonomic symptoms in patients with Parkinson's
disease (PD) and evaluated its reliability and validity. Based on the results of a postal survey …

Parkinson's disease: the non-motor issues

KR Chaudhuri, P Odin, A Antonini… - Parkinsonism & related …, 2011 - Elsevier
Non-motor symptoms (NMS) of Parkinson's disease remain the most under-appreciated and
under-researched when taken as a whole. Data is emerging that it is the “totaL” burden of …

Evidence‐based recommendations for the assessment and management of sleep disorders in older persons

HG Bloom, I Ahmed, CA Alessi… - Journal of the …, 2009 - Wiley Online Library
Sleep‐related disorders are most prevalent in the older adult population. A high prevalence
of medical and psychosocial comorbidities and the frequent use of multiple medications …

Circadian and sleep disorders in Parkinson's disease

A Videnovic, D Golombek - Experimental neurology, 2013 - Elsevier
Impaired sleep and alertness, initially recognized by James Parkinson in his famous
monograph “An Essay on the Shaking Palsy” in 1817, is one of the most common and …