A synopsis on aging—Theories, mechanisms and future prospects

JP da Costa, R Vitorino, GM Silva, C Vogel… - Ageing research …, 2016 - Elsevier
Answering the question as to why we age is tantamount to answering the question of what is
life itself. There are countless theories as to why and how we age, but, until recently, the very …

Key issues in conducting a meta-analysis of gene expression microarray datasets

A Ramasamy, A Mondry, CC Holmes… - PLoS medicine, 2008 - journals.plos.org
Key Issues in Conducting a Meta-Analysis of Gene Expression Microarray Datasets | PLOS
Medicine Skip to main content Advertisement PLOS Medicine Browse Current Issue Journal …

The Immunological Genome Project: networks of gene expression in immune cells

TSP Heng, MW Painter… - Nature …, 2008 - nature.com
The Immunological Genome Project: networks of gene expression in immune cells | Nature
Immunology Skip to main content Thank you for visiting nature.com. You are using a browser …

Repeatability and reproducibility in proteomic identifications by liquid chromatography− tandem mass spectrometry

DL Tabb, L Vega-Montoto, PA Rudnick… - Journal of proteome …, 2010 - ACS Publications
The complexity of proteomic instrumentation for LC-MS/MS introduces many possible
sources of variability. Data-dependent sampling of peptides constitutes a stochastic element …

The MicroArray Quality Control (MAQC) project shows inter-and intraplatform reproducibility of gene expression measurements.

L Shi, LH Reid, WD Jones, R Shippy… - Nature …, 2006 - europepmc.org
Over the last decade, the introduction of microarray technology has had a profound impact
on gene expression research. The publication of studies with dissimilar or altogether …

Effects of sampling regime on the mean and variance of home range size estimates

L Börger, N Franconi, G De Michele, A Gantz… - Journal of Animal …, 2006 - JSTOR
1. Although the home range is a fundamental ecological concept, there is considerable
debate over how it is best measured. There is a substantial literature concerning the …

A modular analysis framework for blood genomics studies: application to systemic lupus erythematosus

D Chaussabel, C Quinn, J Shen, P Patel, C Glaser… - Immunity, 2008 - cell.com
The analysis of patient blood transcriptional profiles offers a means to investigate the
immunological mechanisms relevant to human diseases on a genome-wide scale. In …

Chromatin structure and gene expression programs of human embryonic and induced pluripotent stem cells

MG Guenther, GM Frampton, F Soldner, D Hockemeyer… - Cell stem cell, 2010 - cell.com
Knowledge of both the global chromatin structure and the gene expression programs of
human embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) should …

Development and application of the human intestinal tract chip, a phylogenetic microarray: analysis of universally conserved phylotypes in the abundant microbiota of …

M Rajilić‐Stojanović, HGHJ Heilig… - Environmental …, 2009 - Wiley Online Library
In this paper we present the in silico assessment of the diversity of variable regions of the
small subunit ribosomal RNA (SSU rRNA) gene based on an ecosystem‐specific curated …

[PDF][PDF] Principles of toxicology

DL Eaton, CD Klaassen - Casarett and Doull's Toxicology …, 2001 - courseware.cutm.ac.in
■ Descriptive animal toxicity testing assumes that the e ects produced by a compound in
laboratory animals, when properly quali ed, are applicable to humans, and that exposure o …