Quantitative phase imaging (QPI) is a label-free, wide-field microscopy approach with
significant opportunities for biomedical applications. QPI uses the natural phase shift of light …

Aging induces a series of immune related changes, which is called immunosenescence,
playing important roles in many age-related diseases, especially neurodegenerative …

The COVID pandemic has refreshed and expanded recognition of the vital role that
sustained antibody (Ab) secretion plays in our immune defenses against microbes and of …

Background: The prevalence of non-alcoholic fatty liver disease (NAFLD) keeps growing
recently. Purpose: To investigate the effects and mechanisms of naringenin (NAR) on …

In B cells, IgD is expressed together with IgM through alternative splicing of primary VH DJ
HC μ-sm-Cδ-sm RNAs, and also through IgD class switch DNA recombination (CSR) via …

Aging is associated with the highest risk for morbidity and mortality to chronic or metabolic
diseases, which are present in 50% of the elderly. Improving metabolic and immune function …

Emerging evidence indicates that metabolic programs regulate B cell activation and Ab
responses. However, the metabolic mediators that support the durability of the memory B …

In response to mitogenic stimulation, B cells activate different pro‐anabolic signaling
pathways such as c‐Myc‐and mTORC1‐dependent networks to satisfy the energetic …

Human pluripotent stem cells (hPSCs) can self-renew indefinitely or can be induced to
differentiate. We previously showed that exogenous glutamine (Gln) withdrawal biased …

A large and growing body of evidence supports functions of enzymes that regulate or effect
cellular metabolism in governing the development, survival, and effector functions of …