Improved biological and mechanical functionality of musculoskeletal tissue-engineered
constructs is required for clinical application, which can only be achieved by comprehensive …

Virus-like particles (VLPs) have natural structural antigens similar to those found in viruses,
making them valuable in vaccine immunization. Furthermore, VLPs have demonstrated …

We study patterns of partial synchronization in a network of FitzHugh–Nagumo oscillators
with empirical structural connectivity measured in human subjects. We report the …

During development cells and tissues undergo changes in pattern and form that employ a
wider range of physical mechanisms than at any other time in an organism's life. This book …

Explaining embryonic development of multicellular organisms requires insight into complex
interactions between genetic regulation and physical, generic mechanisms at multiple …

Vasculogenesis, the de novo growth of the primary vascular network from initially dispersed
endothelial cells, is the first step in the development of the circulatory system in vertebrates …

In this paper we present the foundation of a unified, object-oriented, three-dimensional
biomodelling environment, which allows us to integrate multiple submodels at scales from …

We present COMPUCELL3D, a software framework for three-dimensional simulation of
morphogenesis in different organisms. COMPUCELL3D employs biologically relevant …

We describe a 'reactor–diffusion'mechanism for precartilage condensation based on recent
experiments on chondrogenesis in the early vertebrate limb and additional hypotheses …

The evolution of organismal forms consists of the generation, fixation, and variation of
phenotypic characters. The Modern Synthesis concentrated on the last, adaptive variation …