Blood-derived biomarkers for brain and spinal cord diseases are urgently needed. The
introduction of highly sensitive immunoassays led to a rapid increase in the number of …

Traumatic brain injury leads to cellular damage which in turn results in the rapid release of
damage-associated molecular patterns (DAMPs) that prompt resident cells to release …

Introduction: Traumatic brain injury (TBI) is a major worldwide neurological disorder of
epidemic proportions. To date, there are still no FDA-approved therapies to treat any forms …

Blood biomarkers have been explored for their potential to provide objective measures in
the assessment of traumatic brain injury (TBI). However, it is not clear which biomarkers are …

Importance Annually in the United States, at least 3.5 million people seek medical attention
for traumatic brain injury (TBI). The development of therapies for TBI is limited by the …

More than 75% of traumatic brain injuries (TBIs) seeking medical attention are mild, and
outcome in that group is heterogeneous. Until sensitive and valid biomarkers are identified …

Traumatic brain injury (TBI) is the leading cause of death and disability in young adults in the
developed world. The accuracy of early outcome-prediction remains poor even when all …

Abstract HUIBREGTSE, ME, Bazarian, JJ, Shultz, SR, and Kawata K. The biological
significance and clinical utility of emerging blood biomarkers for traumatic brain injury …

Traumatic brain injury (TBI) is a leading cause of morbidity and mortality worldwide. Due to
its high incidence rate and often long-term sequelae, TBI contributes significantly to …

Traumatic brain injury (TBI) remains one of the most complex diseases known in the most
complex of all organs in the body. The causes of TBI are many and varied and include …