Recent advances in the synthesis and biomedical applications of heterocyclic NO-donors

LL Fershtat, ES Zhilin - Molecules, 2021 - mdpi.com
Nitric oxide (NO) is a key signaling molecule that acts in various physiological processes
such as cellular metabolism, vasodilation and transmission of nerve impulses. A wide …

[HTML][HTML] Nitric oxide and hydrogen sulfide regulation of ischemic vascular growth and remodeling

S Rajendran, X Shen, J Glawe, GK Kolluru… - Comprehensive …, 2019 - ncbi.nlm.nih.gov
Ischemic vascular remodeling occurs in response to stenosis or arterial occlusion leading to
a change in blood flow and tissue perfusion. Altered blood flow elicits a cascade of …

Conjugation of bone grafts with NO-delivery dinitrosyl iron complexes promotes synergistic osteogenesis and angiogenesis in rat calvaria bone defects

SH Chang, HY Hsiao, YH Chen, MH Cheng… - Journal of Materials …, 2023 - pubs.rsc.org
Craniofacial/jawbone deformities remain a significant clinical challenge in restoring
facial/dental functions and esthetics. Despite the reported therapeutics for clinical bone …

Endogenous conjugation of biomimetic dinitrosyl iron complex with protein vehicles for oral delivery of nitric oxide to brain and activation of hippocampal …

CR Wu, YD Huang, YH Hong, YH Liu, M Narwane… - Jacs Au, 2021 - ACS Publications
Nitric oxide (NO), a pro-neurogenic and antineuroinflammatory gasotransmitter, features the
potential to develop a translational medicine against neuropathological conditions. Despite …

Combined nitric oxide-releasing poly (vinyl alcohol) film/F127 hydrogel for accelerating wound healing

FS Schanuel, KSR Santos, A Monte-Alto-Costa… - Colloids and Surfaces B …, 2015 - Elsevier
Nitric oxide (NO) releasing biomaterials represent a potential strategy for use as active
wound dressings capable of accelerating wound healing. Topical NO-releasing poly (vinyl …

Nitric oxide-releasing vascular grafts: A therapeutic strategy to promote angiogenic activity and endothelium regeneration

F Kabirian, PB Milan, A Zamanian, R Heying… - Acta biomaterialia, 2019 - Elsevier
Small-diameter vascular grafts (SDVGs) are associated with a high incidence of failure due
to infection and obstruction. Although several vascular grafts are commercially available …

Recent developments in pharmacological effect, mechanism and application prospect of diazeniumdiolates

B Li, Y Ming, Y Liu, H Xing, R Fu, Z Li, R Ni… - Frontiers in …, 2020 - frontiersin.org
Nitric oxide (NO) is a simple structured and unstable free radical molecule, which
participates in the regulation of many pathophysiological processes. It functions both as a …

[HTML][HTML] Beneficial effects of dinitrosyl iron complexes on wound healing compared to commercial nitric oxide plasma generator

A Igrunkova, A Fayzullin, N Serejnikova… - International Journal of …, 2023 - mdpi.com
Nitric oxide (NO) is a gaseous molecule which plays a key role in wound healing.
Previously, we identified the optimal conditions for wound healing strategies using NO …

Proteome differences in placenta and endometrium between normal and intrauterine growth restricted pig fetuses

F Chen, T Wang, C Feng, G Lin, Y Zhu, G Wu… - PLoS …, 2015 - journals.plos.org
Uteroplacental tissue plays a key role in substance exchanges between maternal and fetal
circulation, and, therefore, in the growth and development of fetuses. In this study …

When NO. Is not Enough: Chemical Systems, Advances and Challenges in the Development of NO. and HNO Donors for Old and Current Medical Issues

E Muniz Carvalho, EH Silva Sousa… - European Journal of …, 2021 - Wiley Online Library
Nitric oxide (NO.) has been widely studied as an active agent of many physiological and
pathological processes. Currently, NO. divides attention with its sibling molecule, nitroxyl …