A comprehensive insight into the anti-inflammatory properties of dapsone

M Khalilzadeh, M Shayan, S Jourian, M Rahimi… - Naunyn-Schmiedeberg's …, 2022 - Springer
Abstract The 4, 4′-diaminodiphenyl sulfone (DDS), also known as dapsone, is traditionally
used as a potent anti-bacterial agent in clinical management of leprosy. For decades …

Testicular torsion in vivo models: Mechanisms and treatments

A Minas, S Mahmoudabadi, NS Gamchi… - …, 2023 - Wiley Online Library
Background Testicular torsion is a condition in which a testis rotates around its longitudinal
axis and twists the spermatic cord. This in turn results in a significant decrease in blood flow …

Protective effects of crocin on testicular torsion/detorsion in rats

V Ganjiani, N Ahmadi, MR Divar, H Sharifiyazdi… - Theriogenology, 2021 - Elsevier
Oxidative stress, caused by extreme accumulation of un-scavenged reactive oxygen
species, plays an integral role in the Ischemia-Reperfusion (I/R) injury to the testicles …

Dapsone ameliorates colitis through TLR4/NF-kB pathway in TNBS induced colitis model in rat

RM Jafari, S Shayesteh, M Ala… - Archives of medical …, 2021 - Elsevier
Background Crohn's disease (CD), a type of inflammatory bowel disease (IBD), emerges
with severe gastrointestinal (GI) tract inflammation, sometimes known as hostile abdomen …

Milrinone ameliorates ischaemia‐reperfusion injury in experimental testicular torsion/detorsion rat model

E Kölükçü, D Atılgan, N Uluocak, FA Deresoy… - Andrologia, 2021 - Wiley Online Library
This experimental study aims to evaluate the efficacy of milrinone against ischaemia‐
reperfusion injury due to testicular torsion/detorsion. Group 1 was defined as the control …

Beneficial effects of memantine on ischemia/reperfusion injury following torsion/detorsion induced testicular damage in rats: improvement in histological and …

A Jafari, H Ghasemnejad-Berenji, M Nemati… - Journal of Pediatric …, 2021 - Elsevier
Introduction Testicular torsion is a common urologic emergency and one of the causes of
infertility in males. Hence, prompt diagnosis and treatment are important to prevent testicular …

The effects of pirfenidone on ischaemia–reperfusion injury in testicular torsion‐induced rat model

E Kölükçü, F Firat, FA Deresoy, M Katar, D Atılgan - Andrologia, 2021 - Wiley Online Library
The aim of this study was to analyse the effect of pirfenidone against ischaemia–reperfusion
injury occurring after detorsion in rats with induced testicular torsion model. Group 1 was …

Sinapic acid reduces ischemia/reperfusion injury due to testicular torsion/detorsion in rats

V Unsal, E Kolukcu, F Gevrek, F Firat - Andrologia, 2021 - Wiley Online Library
This study aimed to investigate the protective effect of sinapic acid (SA) on biochemical and
histopathological changes in an experimental testicular torsion‐detorsion rat model. Twenty …

Protective effect of dapsone against renal ischemia-reperfusion injury in rat

S Nezamoleslami, M Sheibani… - …, 2020 - Taylor & Francis
Background: Ischemia/reperfusion can cause injury to tissues and compromise functionality
of organs due to inflammatory processes. Significantly, development of these effects in …

[HTML][HTML] Dapsone, more than an effective neuro and cytoprotective drug

A Diaz-Ruiz, J Nader-Kawachi… - Current …, 2022 - ncbi.nlm.nih.gov
Background Dapsone (4, 4'-diamino-diphenyl sulfone) is a synthetic derivative of sulfones,
with the antimicrobial activity described since 1937. It is also a drug traditionally used in …