Synthesis of naphthoquinone derivatives: menaquinones, lipoquinones and other vitamin K derivatives

M Braasch-Turi, DC Crans - Molecules, 2020 - mdpi.com
Menaquinones are a class of isoprenoid molecules that have important roles in human
biology and bacterial electron transport, and multiple methods have been developed for …

Proline Dehydrogenase and Pyrroline 5 Carboxylate Dehydrogenase from Mycobacterium tuberculosis: Evidence for Substrate Channeling

S Kumar, S Sega, JK Lynn-Barbe, DL Harris, JT Koehn… - Pathogens, 2023 - mdpi.com
In Mycobacterium tuberculosis, proline dehydrogenase (PruB) and∆ 1-pyrroline-5-
carboxylate (P5C) dehydrogenase (PruA) are monofunctional enzymes that catalyze proline …

Exploring Growth of Mycobacterium smegmatis Treated with Anticarcinogenic Vanadium Compounds

Z Arhouma, HA Murakami, JT Koehn, X Li, DA Roess… - Inorganics, 2022 - mdpi.com
A major problem with patient treatments using anticancer compounds is accompanying
bacterial infections, which makes more information on how such compounds impact …

Identification and functional analysis of a new type of Z,E‐mixed prenyl reductase from mycobacteria

T Abe, M Hakamata, A Nishiyama, Y Tateishi… - The FEBS …, 2022 - Wiley Online Library
Isoprenoids with reduced Z, E‐mixed prenyl groups are found in various organisms. To date,
only polyprenol reductases (PR‐Dol) involved in dolichol biosynthesis have been identified …

Interactions of truncated menaquinones in lipid monolayers and bilayers

C Van Cleave, JT Koehn, CS Pereira… - International journal of …, 2021 - mdpi.com
Menaquinones (MK) are hydrophobic molecules that consist of a naphthoquinone
headgroup and a repeating isoprenyl side chain and are cofactors used in bacterial electron …

A Perspective of Diverse Synthetic Approaches and Biological Applications of Vitamin K

S Battula - Vitamin K-Recent Topics on the Biology and …, 2022 - books.google.com
Vitamin-K is a demanding multi-functional health product in the market and belongs to a
class of isoprenoid molecules that comprises methylnaphthoquinone (MK) unit attached to …

Characterization of interactions of lipoquinone derivatives within model membrane systems

GR Bublitz - 2021 - search.proquest.com
Menaquinones (MK) are electron carriers composed of a naphthoquinone moiety and an
isoprene side chain of variable length and saturation. These molecules are the only quinone …