RGD engineered dendrimer nanotherapeutic as an emerging targeted approach in cancer therapy

A Sheikh, S Md, P Kesharwani - Journal of Controlled Release, 2021 - Elsevier
A bird's eye view is now demanded in the area of cancer research to suppress the suffering
of cancer patient and mediate the lack of treatment related to chemotherapy. Chemotherapy …

Oral delivery of RNAi for cancer therapy

H Afrin, R Geetha Bai, R Kumar, SS Ahmad… - Cancer and Metastasis …, 2023 - Springer
Cancer is a major health concern worldwide and is still in a continuous surge of seeking for
effective treatments. Since the discovery of RNAi and their mechanism of action, it has …

[HTML][HTML] Metal-based gels: Synthesis, properties, and applications

G Picci, C Caltagirone, A Garau, V Lippolis… - Coordination Chemistry …, 2023 - Elsevier
This review covers various aspects of recent developments on the design, the synthesis, the
characterization of gels that:(i) are formed in the presence of metal ions (metallogels);(ii) are …

Safety challenges and application strategies for the use of dendrimers in medicine

X Li, A Naeem, S Xiao, L Hu, J Zhang, Q Zheng - Pharmaceutics, 2022 - mdpi.com
Dendrimers are used for a variety of applications in medicine but, due to their host–guest
and entrapment characteristics, are particularly used for the delivery of genes and drugs …

Cutting-edge development in dendritic polymeric materials for biomedical and energy applications

MR Thalji, AA Ibrahim, GAM Ali - European Polymer Journal, 2021 - Elsevier
Dendritic polymers (dendrimers and hyperbranched polymers) are becoming increasingly
popular due to their vast range of uses. Due to their distinctive and novel qualities, they have …

Dendrimer platform against prostate cancer: Recent update on new horizon of treatment

M Pandey, HX Lang, JS Loh, YL Chai, HL Tee… - Journal of Drug Delivery …, 2023 - Elsevier
Prostate malignancy is regarded as one of the most lethal disorders in men. In the last two
decades, new cases of prostate cancer have risen swiftly worldwide. Currently, the …

Engineered dendritic architecture loaded with proton pump inhibitor for antibacterial therapy: Newer solution for gastric upset

N Soni, R Maheshwari, M Sharma… - Journal of Drug Delivery …, 2023 - Elsevier
A majority of gastric malignancies and peptic ulcers are attributed to Helicobacter pylori (H.
pylori), which affects more than 50% of the world's population. A growing number of new …

Hyaluronic acid-protein conjugate modified iron-based MOFs (MIL-101 (Fe)) for efficient therapy of neuroblastoma: Molecular simulation, stability and toxicity studies

AN Nikam, A Pandey, SH Nannuri, G Fernandes… - Crystals, 2022 - mdpi.com
Iron-based metal-organic frameworks (MIL (101)) have recently gained attention in materials
science for biomedical applications. In the present work, Iron-based MOF (MIL-101 (Fe)) …

Engineering of 177Lu-labeled gold encapsulated into dendrimeric nanomaterials for the treatment of lung cancer

Z Wang, M Ye, D Ma, J Shen, F Fang - Journal of Biomaterials …, 2022 - Taylor & Francis
As a novel type of theranostic radioactive agents, 177Lu-labeled nanomaterials conjugated
to macromolecules have been described. The study aimed to fabricate PAMAM-G4–(177Lu …

Expatiating the pivotal role of Dendrimers as emerging nanocarrier for management of Liver Disorders

N Sharma, I Zahoor, S Singh, T Behl… - Journal of Integrated …, 2023 - pubs.thesciencein.org
Despite advancements in medical science, liver disorders remain to be significant global
health challenge, and drug toxicity frequently makes pharmacological therapy difficult …