Endocytosis is a complex process whereby cell surface proteins, lipids and fluid from the
extracellular environment are packaged, sorted and internalized into cells. Endocytosis is …

Our understanding of epithelial-to-mesenchymal transition (EMT) has slowly evolved from a
simple two state, binary model to a multi-step, dynamic continuum of epithelial-to …

Simple Summary Cancer is one of the hardest pathologies to fight, being one of the main
causes of death worldwide despite the constant development of novel therapeutic strategies …

Epithelial-mesenchymal transition (EMT) is a cellular biological process involved in
migration of primary cancer cells to secondary sites facilitating metastasis. Besides, EMT …

Epithelial–mesenchymal plasticity (EMP) plays critical roles during embryonic development,
wound repair, fibrosis, inflammation and cancer. During cancer progression, EMP results in …

Tumor cells undergo invasion and metastasis through epithelial‐to‐mesenchymal cell
transition (EMT) by activation of alterations in extracellular matrix (ECM) protein‐encoding …

Epithelial–mesenchymal transitions (EMTs) generate hybrid phenotypes with an enhanced
ability to adapt to diverse microenvironments encountered during the metastatic spread …

Metastasis, therapy failure and tumour recurrence are major clinical challenges in cancer.
The interplay between tumour‐initiating cells (TICs) and epithelial–mesenchymal transition …

Cancer-associated fibroblasts (CAFs) play an important role in the initiation, metastasis, and
invasion of breast cancer. However, whether autophagy acts as a tumor promotion …

The yes-associated protein (YAP) and the transcriptional coactivator with PDZ-binding motif
(TAZ) are transcriptional coactivators, members of the Hippo signaling pathway, which play …