Metabolic Engineering of Escherichia coli for De Novo Production of 1,2-Butanediol

N Qin, F Zhu, Y Liu, D Liu, Z Chen - ACS Synthetic Biology, 2023 - ACS Publications
1, 2-Butanediol (1, 2-BDO) is an important platform chemical widely utilized in the synthesis
of polyester polyols, plasticizers, cosmetics, and pharmaceuticals. However, no natural …

Achieving high titer and yield in the bioconversion of l-threonine to 2-hydroxybutyric acid with Escherichia coli BL21

T Le, BF Bassey, TP Nguyen-Vo, S Park - Systems Microbiology and …, 2024 - Springer
The study investigated the enhanced production of 2-hydroxybutyric acid (2-HBA) from
threonine using a two-step whole-cell bioconversion by recombinant Escherichia coli BL21 …

Whole-Cell Display of Phosphotransferase in Escherichia coli for High-Efficiency Extracellular ATP Production

S Zhao, G Yang, X Xie, G Yan, F Wang, W Chen, L Ma - Biomolecules, 2022 - mdpi.com
Adenosine triphosphate (ATP), as a universal energy currency, takes a central role in many
biochemical reactions with potential for the synthesis of numerous high-value products …

Re-introduction of endogenous pathways for propionyl-CoA, 1-propanol and propionate formation in Escherichia coli

T Le - bioRxiv, 2021 - biorxiv.org
In a previous study, we found that 2-ketobutyrate (2-KB) was seriously degraded in
Escherichia coli. In the present investigation, we tried to clarify the products of that …