Genetically encoded fluorescent biosensors have revolutionized the study of cell signaling
and metabolism, as they allow for live-cell measurements with high spatiotemporal …

Molecularly generated light, referred to here as “molecular light”, mainly includes
bioluminescence, chemiluminescence, and Cerenkov luminescence. Molecular light …

Cell signaling networks are intricately regulated in time and space to determine the
responses and fates of cells to different cues. Genetically encodable fluorescent and …

Neural circuits and the cells that comprise them represent the functional units of the brain.
Circuits relay and process sensory information, maintain homeostasis, drive behaviors, and …

Developmental patterning is essential for regulating cellular events such as axial patterning,
segmentation, tissue formation, and organ size determination during embryogenesis …

Genetically encoded optical sensors and advancements in microscopy instrumentation and
techniques have revolutionized the scientific toolbox available for probing complex …

The use of bioluminescence as a reporter for physiology in neuroscience is as old as the
discovery of the calcium-dependent photon emission of aequorin. Over the years …

Bioluminescent systems are increasingly being used for the development of highly sensitive
optical imaging techniques in vivo. However, it is necessary to inject expensive and unstable …