Members of the family Herpesviridae have enveloped, spherical virions with characteristic
complex structures consisting of symmetrical and non-symmetrical components. The linear …

Viruses account for 80% of all cases of acute conjunctivitis and adenovirus; enterovirus and
herpes virus are the common causative agents. In general, viral conjunctivitis spreads …

Antibiotic resistance against infections caused by microbes has emerged as a global
challenge resulting in longer hospitalizations and higher medical cost and mortality. The …

To initiate infection, many viruses enter their host cells by triggering endocytosis following
receptor engagement. However, the mechanisms by which non-enveloped viruses escape …

How the human cytomegalovirus (HCMV) genome—the largest among human
herpesviruses—is packaged, retained, and ejected remains unclear. We present the in situ …

Knowledge about viral characteristics, mechanisms of entry into the host cell and
multiplication/dissemination can help in the control and treatment of viral pathologies …

Many viruses previously have been shown to have pressurized genomes inside their viral
protein shell, termed the capsid. This pressure results from the tight confinement of …

Highlights•Dynein and kinesin-1.•Importin α, importin β, nuclear pores, and
nucleoporins.•BoHV-1, HSV-1, PrV, and VZV.Microtubule transport and nuclear import are …

During viral replication, herpesviruses utilize a unique strategy, termed nuclear egress, to
translocate capsids from the nucleus into the cytoplasm. This initial budding step transfers a …

Herpes simplex viruses (HSVs) cause human oral and genital ulcer diseases. Patients with
HSV-2 have a higher risk of acquiring a human immunodeficiency virus infection. HSV-2 is a …