Since the first dendrimer was reported in 1978 by Fritz Vögtle, dendrimer research has
grown exponentially, from synthesis to application in the past four decades. The distinct …

Drug delivery systems or vectors are usually needed to improve the bioavailability and
effectiveness of a drug through improving its pharmacokinetics/pharmacodynamics at an …

Controlled drug delivery systems (DDS) have several advantages compared to the
traditional forms of drugs. A drug is transported to the place of action, hence, its influence on …

Dendrimers, as a type of artificial polymers with unique structural features, have been
extensively explored for their applications in biomedical fields, especially in drug delivery …

Drugs are introduced into the body by numerous routes such as enteral (oral, sublingual and
rectum administration), parenteral (intravascular, intramuscular, subcutaneous and …

As our understanding of the physiopathology of intervertebral disc (IVD) degeneration has
improved, novel therapeutic strategies have emerged, based on the local injection of cells …

There is always a need for alternative and efficient methods of drug delivery. The nasal
cavity can be considered as a non-invasive and efficient route of administration. It has been …

For cancer nanomedicine, the main goal is to deliver therapeutic agents effectively to solid
tumors. Here, we report the unique design of self-adaptive ultrafast charge-reversible …

Berberine (BBR) is a nitrogenous cyclic natural alkaloid with potential anticancer activity.
However it has been less explored due to its poor pharmacokinetic profile. Dendrimers (eg …

Poly (amidoamine)(PAMAM) dendrimers are promising multipotent gene delivery vectors,
providing favorable DNA condensation properties also in combination with the possibility of …