Asthma—Genomic Advances Toward Risk Prediction

E Herrera-Luis, M Martin-Almeida… - Clinics in chest …, 2024 - chestmed.theclinics.com
Technological advances have accelerated discoveries in human genetics, including risk
variant identification, genetic risk prediction, and functional assessment of genetic variation …

Multi-omic association study identifies DNA methylation-mediated genotype and smoking exposure effects on lung function in children living in urban settings

M Dapas, EE Thompson, W Wentworth-Sheilds… - PLoS …, 2023 - journals.plos.org
Impaired lung function in early life is associated with the subsequent development of chronic
respiratory disease. Most genetic associations with lung function have been identified in …

Admixture mapping of severe asthma exacerbations in Hispanic/Latino children and youth

E Herrera-Luis, ACY Mak, J Perez-Garcia… - Thorax, 2023 - thorax.bmj.com
Background In the USA, genetically admixed populations have the highest asthma
prevalence and severe asthma exacerbations rates. This could be explained not only by …

Targeted analysis of genomic regions enriched in African ancestry reveals novel classical HLA alleles associated with asthma in Southwestern Europeans

E Suarez-Pajes, C Díaz-García, H Rodríguez-Pérez… - Scientific Reports, 2021 - nature.com
Despite asthma has a considerable genetic component, an important proportion of genetic
risks remain unknown, especially for non-European populations. Canary Islanders have the …

Asthma-Genomic Advances Toward Risk

AT Risk - Pediatric Respiratory Disease, an Issue of Clinics in …, 2024 - books.google.com
• Genome-wide association studies of asthma have unraveled a wide catalog of common
variants associated with asthma with small to-moderate effect sizes. Further efforts should be …