The complexity of nanoscale interactions between biomaterials and cells has limited the
realization of the ultimate vision of nanotechnology in diagnostics and therapeutics. As such …

Extracellular vesicles (EVs), a term that includes both exosomes of endocytic origin and
vesicles derived from plasma membranes, are continuously secreted by cells to the …

Exosomes are released by most cells to the extracellular environment and are involved in
cell-to-cell communication. Exosomes contain specific repertoires of mRNAs, microRNAs …

Cells respond to inflammatory disease states by releasing exosomes containing highly
specific protein and RNA cargos, but how inflammation alters cargo specificity and secretion …

Stress proteins (SPs) including heat-shock proteins (HSPs), RNA chaperones, and ER
associated stress proteins are molecular chaperones essential for cellular homeostasis. The …

Extracellular vesicles (EVs) are a heterogeneous population of secreted membrane
vesicles, with distinct biogenesis routes, biophysical properties and different functions both …

The hnRNPs (heterogeneous nuclear ribonucleoproteins) are RNA-binding proteins with
important roles in multiple aspects of nucleic acid metabolism, including the packaging of …

Extracellular vesicles are small membrane particles derived from various cell types. EVs are
broadly classified as ectosomes or small extracellular vesicles, depending on their …

Late endosomes and lysosomes are dynamic organelles that constantly move and fuse to
acquire cargo from early endosomes, phagosomes and autophagosome. Defects in …

Cesium chloride (CsCl)-and iodixanol-based density gradients represent the core step in
most protocols for serotype-independent adeno-associated virus (AAV) purification …