Cells utilize diverse ATP-dependent nucleosome-remodelling complexes to carry out
histone sliding, ejection or the incorporation of histone variants, suggesting that different …

Macromolecular assemblies that regulate chromatin structure using the energy of ATP
hydrolysis have critical roles in development, cancer, and stem cell biology. The ATPases of …

Chromatin consists of a complex of DNA and histone proteins as its core components and
plays an important role in both packaging DNA and regulating DNA metabolic pathways …

Over the past 10 years, the study of histone acetyltransferases (HATs) has advanced
significantly, and a number of HATs have been isolated from various organisms. It emerged …

The Snf2 family of helicase-related proteins includes the catalytic subunits of ATP-
dependent chromatin remodelling complexes found in all eukaryotes. These act to regulate …

Set2 methylates Lys36 of histone H3. We show here that yeast Set2 copurifies with RNA
polymerase II (RNAPII). Chromatin immunoprecipitation analyses demonstrated that Set2 …

Nrf2 is a transcription factor critical for the maintenance of cellular redox homeostasis. We
have previously found that Nrf2 is a labile protein, and its activation in cells under stress …

We present an analysis of over 1,100 of the∼ 10,000 predicted proteins encoded by the
genome sequence of the filamentous fungus Neurospora crassa. Seven major areas of …

Appreciable advances into the process of transcript elongation by RNA polymerase II (RNAP
II) have identified this stage as a dynamic and highly regulated step of the transcription …

Methylation of cytosines within the CpG dinucleotide by DNA methyltransferases is involved
in regulating transcription and chromatin structure, controlling the spread of parasitic …